Abakumov M M, Abrosimov V A, Markova O A, Khvatov V B
Khirurgiia (Mosk). 1998(1):15-8.
3 groups of 37 patients were examined, in which for treatment of spontaneous pneumothorax drainage of pleural cavity and medicamentous pleurodesis with tetracycline hydrochloride and 4% solution of sodium bicarbonate were used. Interdependence of clinical criteria and level of protease inhibitors were evaluated, as well as the basic components of hemostasis. The best effectiveness of treatment in carrying out chemical pleurodesis was demonstrated, especially when 4% sodium bicarbonate solution was used. At the same time the application of this agent has evoked the most evident changes in values of hemostasis and protease inhibitors. The possibility of use of the above mentioned biochemical in dices together with clinical criteria for the evaluation of effectiveness of treatment of the unspecific spontaneous pneumothorax is stressed.
对3组每组37例患者进行了检查，其中采用胸腔引流及用盐酸四环素和4%碳酸氢钠溶液进行药物性胸膜固定术治疗自发性气胸。评估了临床标准与蛋白酶抑制剂水平之间的相互关系以及止血的基本成分。结果表明，进行化学性胸膜固定术时治疗效果最佳，尤其是使用4%碳酸氢钠溶液时。同时，使用该药物引起了止血和蛋白酶抑制剂值最明显的变化。强调了将上述生化指标与临床标准一起用于评估非特异性自发性气胸治疗效果的可能性。
