Solomons N W, Wagonfeld J B, Thomsen S, Hill J L, Kirsner J B
Pediatrics. 1976 Aug;58(2):268-73.
An unusual incidence of a duodenal leiomyosarcoma in a 10-year-old boy is presented. The corrected diagnosis was made after a 27-month course of occult gastrointestinal bleeding, vague abdominal complaints, and anemia. Gastrointestinal radiography and upper gastrointestinal endoscopy were useful in localizing the lesion. The tumor was removed at exploratory surgery by simple excision. On frozen section, the tumor was thought to be benign, but fixed microscopic histological sections revealed a well-differentiated, malignant smooth muscle tumor. The presentation of this tumor in a child is compared to previously reported cases in adults, and the biological and clinical characteristics of malignant smooth muscle tumors of the gastrointestinal tract are reviewed.
本文报道了一名10岁男孩发生十二指肠平滑肌肉瘤的罕见病例。经过27个月的隐匿性胃肠道出血、腹部隐痛不适及贫血病程后才做出正确诊断。胃肠造影和上消化道内镜检查有助于确定病变部位。在探查性手术中通过单纯切除将肿瘤切除。冰冻切片时，肿瘤被认为是良性的，但固定后的显微镜组织学切片显示为高分化恶性平滑肌瘤。将该肿瘤在儿童中的表现与先前报道的成人病例进行了比较，并对胃肠道恶性平滑肌瘤的生物学和临床特征进行了综述。
