Dreyer W P, Basson N J
Department of Oral Medicine and Periodontics, University of Stellenbosch, Tygerberg.
J Dent Assoc S Afr. 1992 Dec;47(12):513-6.
Ovine periodontitis has clinical features similar to early onset periodontitis in man. Porphyromonas gingivalis has been implicated as a putative pathogen in this disease and its role in periodontitis in 107 sheep was investigated. The organism was recovered from most diseased sites at a significant percentage level of the total bacterial count. Antibody assays of 107 animals using an ELISA did not distinguish between diseased (46) and control adult (33) sheep for either P. gingivalis or any of the other putative periodontopathogens tested, but did differentiate adult sheep from healthy lambs (28) for all bacteria except one. It is suggested that sheep rather than human bacterial strains should be used in antibody studies of ovine periodontitis.
绵羊牙周炎具有与人类早发性牙周炎相似的临床特征。牙龈卟啉单胞菌被认为是这种疾病的一种假定病原体，对其在107只绵羊牙周炎中的作用进行了研究。从大多数患病部位分离出该菌，其在细菌总数中所占比例显著。使用酶联免疫吸附测定法对107只动物进行抗体检测，对于牙龈卟啉单胞菌或所检测的任何其他假定牙周病原体，患病绵羊（46只）和对照成年绵羊（33只）之间没有区别，但除一种细菌外，对于所有细菌，成年绵羊与健康羔羊（28只）之间存在差异。建议在绵羊牙周炎的抗体研究中应使用绵羊而非人类的细菌菌株。
