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创伤后应激障碍患者的抑郁亚型划分

Depression subtyping in PTSD patients.

作者信息

Constans J I, Lenhoff K, McCarthy M

机构信息

New Orleans Veterans Affairs Medical Center, Louisiana 70146, USA.

出版信息

Ann Clin Psychiatry. 1997 Dec;9(4):235-40. doi: 10.1023/a:1022304410404.

DOI:10.1023/a:1022304410404
PMID:9511947
Abstract

A Structured Clinical Interview for the DSM-IV (SCID) and psychological testing were administered to 260 combat veterans in order to investigate the relationship between symptoms of post-traumatic stress disorder (PTSD) and melancholic features of depression. Sixty-seven percent of PTSD patients experiencing comorbid major depression acknowledged symptoms indicative of a melancholic-depression subtype. Correlational and regression analyses show that the presence of melancholic features is related to severity of emotional-numbing experienced by the PTSD patients. These results suggest PTSD patients are likely to experience depressive episodes phenomenologically similar to melancholic-depression. It is likely that acknowledgment of melancholic symptoms is due to (a) the inclusion of guilt as a melancholic feature, and (b) the similarities between emotional numbing symptoms and other melancholic features.

摘要

为了研究创伤后应激障碍(PTSD)症状与抑郁症的忧郁特征之间的关系,对260名退伍军人进行了《精神疾病诊断与统计手册》第四版(DSM-IV)的结构化临床访谈(SCID)和心理测试。67%患有共病重度抑郁症的PTSD患者承认有表明忧郁症-抑郁症亚型的症状。相关分析和回归分析表明,忧郁特征的存在与PTSD患者经历的情感麻木严重程度有关。这些结果表明,PTSD患者可能会经历在现象学上与忧郁症-抑郁症相似的抑郁发作。忧郁症状的出现可能是由于:(a)将内疚作为忧郁特征之一,以及(b)情感麻木症状与其他忧郁特征之间的相似性。

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