Siemion I Z, Strug I, Szewczuk Z
Department of Chemistry, University of Wrocław, Poland.
Acta Biochim Pol. 1997;44(3):519-25.
The biologically active conformation of thymopoietin, based on X-ray data reported for discontinuous thymopoietin-like motif of G-actin, is proposed. The conformation is compared with that resulting from the prediction made by the method of Chou & Fasman (Annu. Rev. Biochem. 47, 251-276, 1978) and Rost & Sander (Methods Enzymol. 266, 525-539, 1996).
基于报道的G-肌动蛋白不连续胸腺生成素样基序的X射线数据，提出了胸腺生成素的生物活性构象。将该构象与用Chou & Fasman方法（《生物化学年度评论》47卷，251 - 276页，1978年）和Rost & Sander方法（《酶学方法》266卷，525 - 539页，1996年）预测得到的构象进行了比较。
