Hu T, Fan B, Liang J, Zhao S, Dang P, Gao F, Dong M
Institute of Traditional Chinese Veterinary Medicine, Chinese Academy of Agricultural Sciences, Lanzhou, People's Republic of China.
Trop Anim Health Prod. 1997 Nov;29(4 Suppl):72S-76S. doi: 10.1007/BF02632936.
Eighty two cattle naturally infected with haemosporidians were treated with total alkaloid hydrochloride of Peganum harmale L. (0.5 mg/kg/day). Fifty eight cases with Theileria sergenti showed a cure rate of 86%; thirteen cases with Theileria annulata showed a cure rate of 85%; eight cattle infected with Babesia bigemina showed a cure rate of 88% and three cases of Anaplasma marginale were completely cured. The results suggested that the curative effect of total alkaloid of P. harmale was better than that of diminazene aceturate and produced minimal side effects. The alkaloid could also be administered to pregnant animals. It was concluded that the total alkaloid of P. harmale showed a marked effect as a treatment for haemosporidican infections in cattle.
对82头自然感染血孢子虫的牛，用骆驼蓬总生物碱盐酸盐（0.5毫克/千克/天）进行治疗。58例感染瑟氏泰勒虫的病例治愈率为86%；13例感染环形泰勒虫的病例治愈率为85%；8头感染双芽巴贝斯虫的牛治愈率为88%，3例边缘无浆体感染的病例完全治愈。结果表明，骆驼蓬总生物碱的治疗效果优于贝尼尔，且副作用极小。该生物碱也可用于妊娠动物。结论是，骆驼蓬总生物碱对牛血孢子虫感染有显著的治疗效果。
