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两例与Ⅰ型神经纤维瘤病相关的蛛网膜下腔出血:一例为多发性脑动脉瘤和动静脉畸形,另一例为前交通动脉瘤

[Two cases of subarachnoid hemorrhage associated with neurofibromatosis type I: a case of multiple cerebral aneurysms and arteriovenous malformation, and another case of an anterior communicating artery aneurysm].

作者信息

Oyama H, Nakane T, Handa T, Mizutani N, Ikeda K, Inoue S, Shibuya M, Doi A

机构信息

Department of Neurosurgery, Chukyo Hospital, Nagoyashi, Japan.

出版信息

No Shinkei Geka. 1998 Feb;26(2):151-6.

PMID:9513196
Abstract

Two cases of subarachnoid hemorrhage associated with neurofibromatosis type I (von Recklinghausen's disease) are reported. A 30-year-old male patient (case 1) had been diagnosed as having neurofibromatosis type I due to neurofibroma and café-au-lait spot. He suffered from subarachnoid hemorrhage and angiography showed multiple aneurysms in the right and left middle cerebral arteries and left internal carotid artery. He also had arteriovenous malformation in the left temporal lobe. Case 2 was that of a 62-year-old female patient with neurofibroma and café-au-lait spot. She suffered from subarachnoid hemorrhage and angiography showed an aneurysm in the anterior communicating artery. Both patients were discharged with no deficits after neck clipping, however they both suffered from large-sized hematoma in the punctured site of the femoral artery after angiography. The cerebral aneurysms associated with neurofibromatosis type I are often multiple and may coexist with arteriovenous malformation.

摘要

报告了两例与Ⅰ型神经纤维瘤病(冯·雷克林豪森病)相关的蛛网膜下腔出血病例。一名30岁男性患者(病例1)因神经纤维瘤和咖啡斑被诊断为患有Ⅰ型神经纤维瘤病。他发生了蛛网膜下腔出血,血管造影显示右侧和左侧大脑中动脉以及左侧颈内动脉有多个动脉瘤。他在左侧颞叶还有动静脉畸形。病例2是一名62岁女性患者,有神经纤维瘤和咖啡斑。她发生了蛛网膜下腔出血,血管造影显示前交通动脉有一个动脉瘤。两名患者在颈部夹闭术后均无神经功能缺损出院,但他们在血管造影后股动脉穿刺部位均出现了巨大血肿。与Ⅰ型神经纤维瘤病相关的脑动脉瘤通常为多发,且可能与动静脉畸形并存。

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