Tomita K, Suyama A, Igawa K, Katou K, Yamasaki A, Kometani Y, Sano H, Nagata K, Sasaki T
Third Department of Internal Medicine, Faculty of Medicine, Tottori University, Japan.
J Asthma. 1998;35(1):79-87. doi: 10.3109/02770909809055408.
The aim of this study was to determine which background variables exert the most influence on airway responsiveness in adult asthmatic patients. The relationships between airway response and background variables were investigated by multiple linear and logistic regression analysis in 97 asthmatic patients. Airway responsiveness was measured by the oscillation technique during methacholine inhalation challenge. The regression analyses revealed that modified Aas score "one of asthma severity score", was the major factor contributing to airway hyperreactivity. We conclude that the number of attacks during a previous year is the most important background factor related to airway hyperresponsiveness on a clinical basis.
本研究的目的是确定哪些背景变量对成年哮喘患者的气道反应性影响最大。通过对97例哮喘患者进行多元线性和逻辑回归分析，研究气道反应性与背景变量之间的关系。在乙酰甲胆碱吸入激发试验期间，采用振荡技术测量气道反应性。回归分析显示，改良的阿斯评分（哮喘严重程度评分之一）是导致气道高反应性的主要因素。我们得出结论，基于临床情况，前一年的发作次数是与气道高反应性相关的最重要背景因素。
