恶性组织细胞增多症的联合化疗
Combination chemotherapy of malignant histiocytosis.
作者信息
Palazzo E, Bergerat J P, Vetter J M, Boilletot A, Lang J M, Oberling F
出版信息
Acta Haematol. 1979;62(5-6):251-6. doi: 10.1159/000207583.
PMID:95146
Abstract
Three patients with malignant histiocytosis treated with combination chemotherapy are reported. Induction treatment included bleomycin, adriamycin, cyclophosphamide, vincristine and prednisone (BACOP). Complete response was obtained in one patient who is alive and well 32 months after diagnosis. A partial response was obtained in the second patient, who is alive and well 35 months after diagnosis. The third patient died with drug-induced agranulocytosis and sepsis.
摘要
报告了3例接受联合化疗的恶性组织细胞增多症患者。诱导治疗包括博来霉素、阿霉素、环磷酰胺、长春新碱和泼尼松（BACOP方案）。1例患者获得完全缓解，诊断后32个月仍存活且状况良好。第2例患者获得部分缓解，诊断后35个月仍存活且状况良好。第3例患者死于药物性粒细胞缺乏症和败血症。
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