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多胎妊娠减胎术后进行基因羊水穿刺检查不会增加流产风险。

Genetic amniocentesis following multifetal pregnancy reduction does not increase the risk of pregnancy loss.

作者信息

McLean L K, Evans M I, Carpenter R J, Johnson M P, Goldberg J D

机构信息

Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco 94143-0720, USA.

出版信息

Prenat Diagn. 1998 Feb;18(2):186-8.

PMID:9516022
Abstract

A collaborative, retrospective study of patients who had undergone multifetal pregnancy reduction (MFPR) to twins and subsequent genetic amniocentesis was performed to determine if amniocentesis increased the risk of pregnancy loss. Seventy-nine patients from three centres underwent MFPR and subsequent amniocentesis. The pregnancy loss rate was 5.06 per cent in this group. In comparison, the loss rate from a control collaborative series of patients who underwent MFPR only was 11.19 per cent, which was not statistically different. Thus, it appears that amniocentesis following MFPR is unlikely to increase the pregnancy loss rate.

摘要

对接受多胎妊娠减胎术(MFPR)减至双胎并随后进行遗传羊膜腔穿刺术的患者进行了一项合作性回顾性研究,以确定羊膜腔穿刺术是否会增加流产风险。来自三个中心的79名患者接受了MFPR及随后的羊膜腔穿刺术。该组的流产率为5.06%。相比之下,仅接受MFPR的对照合作系列患者的流产率为11.19%,两者在统计学上无差异。因此,看来MFPR后进行羊膜腔穿刺术不太可能增加流产率。

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