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植物对病原体作出反应时的转录和转录后基因沉默

Transcriptional and posttranscriptional plant gene silencing in response to a pathogen.

作者信息

Al-Kaff NS, Covey SN, Kreike MM, Page AM, Pinder R, Dale PJ

机构信息

John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, UK.

出版信息

Science. 1998 Mar 27;279(5359):2113-5. doi: 10.1126/science.279.5359.2113.

DOI:10.1126/science.279.5359.2113
PMID:9516113
Abstract

Plants are able to respond to pathogen attack to restrain development of a systemic infection. The response of Brassica napus (oilseed rape) to systemic infection with the DNA virus cauliflower mosaic virus was shown to result in enhancement and subsequent suppression of viral gene expression in parallel with changes in symptom expression. Transgenes with homology to viral sequences were also affected. This phenomenon, which was shown to be mediated by both transcriptional and posttranscriptional mechanisms, might be related to regulation of highly expressed genetic elements.

摘要

植物能够对病原体攻击做出反应,以抑制系统性感染的发展。研究表明,甘蓝型油菜(油菜籽)对DNA病毒花椰菜花叶病毒的系统性感染反应,会导致病毒基因表达先增强随后受到抑制,同时症状表达也发生变化。与病毒序列具有同源性的转基因也受到影响。这一现象被证明是由转录和转录后机制介导的,可能与高表达遗传元件的调控有关。

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