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[细胞内钾浓度降低时培养基中钾浓度与肌纤维膜电位之间的“异常”关系。III. 在含有2.5或75 mM钾的蔗糖 - 硫酸盐培养基中长时间孵育肌肉期间膜电位的变化]

[The "anomalous" relationship between the concentration of potassium in the medium and the membrane potential of muscle fibers with a decreased intracellular potassium concentration. III. Change in the membrane potential during prolonged muscle incubation in saccharose-sulfate media containing 2.5 or 75 mM of potassium].

作者信息

Vereninov A A, Vinogradova T A, Toropova F V

出版信息

Tsitologiia. 1976 Feb;18(2):195-202.

PMID:951741
Abstract

At the external potassium concentration 2.5 mM, The value Em--Ek diminishes, but at 75 mM it increases, although the potassium fluxes are nearly balanced and nosignificant changes in internal potassium occur. The contribution of other ions to the electrogenesis is examined. An attempt is made to describe the movement of these ions by the Goldman equations. The permeability coeficients should have been much higher than potassium coefficient, and besides it should be admitted that the coefficients and the internal activity of ions discussed may vary with time.

摘要

在外部钾离子浓度为2.5 mM时,Em - Ek的值减小,但在75 mM时它会增加,尽管钾离子通量几乎平衡且细胞内钾离子没有显著变化。研究了其他离子对电发生的贡献。尝试用戈德曼方程描述这些离子的运动。渗透系数应该比钾离子系数高得多,此外应该承认所讨论的离子系数和内部活性可能随时间变化。

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