Petrulis A, DeSouza I, Schiller M, Johnston R E
Department of Psychology, Cornell University, Ithaca, New York 14853, USA.
Behav Neurosci. 1998 Feb;112(1):199-212. doi: 10.1037//0735-7044.112.1.199.
Orbital/agranular insular (ORB/AI) cortex has been implicated in traditional olfactory learning tasks and social behavior but its precise role in discriminating-learning social odors is not known. Female golden hamsters received aspiration lesions of ORB/AI or dorsomedial (DM) frontal cortex and were tested for their ability to (a) discriminate between odors of individual males in a habituation-discrimination task, (b) show preferences for male over female odors, and (c) scent-mark in response to male odors. Lesioned females readily discriminated between scents of individual males. Neither lesion altered female preferences for male odors. Females with DM lesions showed increased levels of scent marking to male odors, but those with ORB/AI cortex lesions did not differ from controls. Thus, ORB/AI cortex does not appear to be critical for discrimination of odors of individuals or sex or for scent-marking responses based on these discriminations.
眶额/无颗粒岛叶（ORB/AI）皮质已被证明与传统嗅觉学习任务和社会行为有关，但其在辨别性学习社会气味方面的确切作用尚不清楚。雌性金黄地鼠接受了ORB/AI或背内侧（DM）额叶皮质的损毁，并测试它们（a）在习惯化-辨别任务中区分个体雄性气味的能力，（b）对雄性气味而非雌性气味表现出偏好的能力，以及（c）对雄性气味做出气味标记反应的能力。损毁后的雌性能够轻松区分个体雄性的气味。两种损毁都没有改变雌性对雄性气味的偏好。DM损毁的雌性对雄性气味的气味标记水平增加，但ORB/AI皮质损毁的雌性与对照组没有差异。因此，ORB/AI皮质对于辨别个体气味或性别气味，或基于这些辨别的气味标记反应似乎并不关键。
