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[破骨性手指关节病——手部多关节病的一种亚型]

[Osteoclastic finger arthrosis--a subtype of hand polyarthrosis].

作者信息

Dihlmann W, Dihlmann A

机构信息

Radiologische Praxis Hamburg-Barmbek.

出版信息

Rofo. 1998 Feb;168(2):128-32. doi: 10.1055/s-2007-1015196.

DOI:10.1055/s-2007-1015196
PMID:9519043
Abstract

AIM

Description of a subtype of arthrosis deformans of the hand which is characterised as osteoclastic arthrosis.

PATIENTS AND METHODS

Retrospective analysis of radiographs of the hands of 150 women and 100 men with radiological findings of arthrosis deformans.

RESULTS

5% of women and 2% of men showed at least one digital joint with subchondral osteolysis of one or both articulating bones involving at least a third of the phalanx. This subchondral osteolysis far exceeds the cysts which are situated in the epiphyseal part of the articular region. It may develop within a year.

CONCLUSION

Osteoclastic arthrosis of the finger is a subtype of polyarthrosis of the hand. Serial observations suggest that an osteoclast stimulating substance is produced by the cysts or arises directly from the synovial fluid; this enters the subchondral part of the bone through clefts which may or may not be visible radiologically and that this produces osteoclastic activity. The most important differential diagnoses are chronic tophaceous gout and a benign tumor.

摘要

目的

描述一种手部变形性关节病的亚型,其特征为破骨性关节病。

患者与方法

对150名女性和100名男性手部X线片进行回顾性分析,这些患者均有变形性关节病的放射学表现。

结果

5%的女性和2%的男性至少有一个指关节出现一个或两个关节面骨的软骨下骨溶解,累及至少三分之一的指骨。这种软骨下骨溶解远远超过位于关节区域骨骺部分的囊肿。它可能在一年内发展。

结论

手指破骨性关节病是手部多关节病的一种亚型。系列观察表明,囊肿产生一种破骨细胞刺激物质,或直接从滑液中产生;该物质通过可能在放射学上可见或不可见的裂隙进入骨的软骨下部分,并产生破骨细胞活性。最重要的鉴别诊断是慢性痛风石性痛风和良性肿瘤。

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