Moritz J D, Westerhof J P, Funke M, Breiter N, Oestmann J W, Grabbe E
Abteilung Röntgendiagnostik, Klinikum, Georg-August-Universität Göttingen.
Rofo. 1998 Feb;168(2):133-8. doi: 10.1055/s-2007-1015197.
A radiography system specially developed for specimen radiography and allowing maximal 20-fold magnification is presented. The efficiency of the system was tested and compared with that of conventional magnification mammography systems.
23 surgical and 90 core biopsies of the breast were examined for detection of microcalcifications. As criteria the number of identifiable calcifications, their shape and configuration as well as tissue contrast were chosen.
The new technique detected about 400% more microcalcifications, 200% more core and 50% more surgical biopsies containing calcifications. Thus, in a few cases, additional core biopsies were unnecessary. Moreover, this new system yielded additional information for the pathologist and surgeon concerning the exact localisation of suspicious lesions that facilitated working up specimens, or indicated additional surgical removal in special cases.
By identification of malignant lesions not detectable with conventional magnification radiography systems, as well as a more exact localisation of suspicious lesions, false negative results may be reduced.
介绍一种专门为标本射线照相开发的射线照相系统,其最大放大倍数可达20倍。测试了该系统的效率,并与传统放大乳腺摄影系统的效率进行了比较。
对23例乳腺手术活检和90例粗针活检进行检查,以检测微钙化。选择可识别的钙化数量、其形状和形态以及组织对比度作为标准。
新技术检测到的微钙化数量多出约400%,含有钙化的粗针活检多出200%,手术活检多出50%。因此,在少数情况下,无需额外进行粗针活检。此外,该新系统为病理学家和外科医生提供了有关可疑病变确切定位的额外信息,有助于处理标本,或在特殊情况下指示进行额外的手术切除。
通过识别传统放大射线照相系统无法检测到的恶性病变,以及更精确地定位可疑病变,可减少假阴性结果。