Hoss D, Segal S
Department of Dermatology, University of Connecticut Health Center, Farmington 06030, USA.
Arch Dermatol. 1998 Mar;134(3):327-30. doi: 10.1001/archderm.134.3.327.
Cutaneous dysesthesia syndrome is a disorder characterized by chronic cutaneous symptoms without objective findings. Patients complain of burning, stinging, or itching, which is often triggered or exacerbated by psychological or physical stress. These symptoms may be manifestations of an underlying psychiatric disorder or may represent a type of chronic pain syndrome.
Eleven women presented with chronic severe pain and/or pruritus of the scalp only without objective physical findings, a condition we term "scalp dysesthesia." Five women described pain, stinging, or burning only; 4 women complained of pain and pruritus; and 2 women reported pruritus only. The patients ranged in age from 36 to 70 years. The duration of symptoms ranged from 9 months to 7 years. Five women had physician-diagnosed psychiatric disorders, including dysthymic disorder, generalized anxiety, and somatization. Seven women reported that stress triggers or exacerbates their symptoms. Eight women experienced improvement or complete resolution of symptoms with treatment with low-dose doxepin hydrochloride or amitriptyline hydrochloride. One patient responded completely to treatment with sertraline and hydroxyzine hydrochloride but then experienced a relapse.
We describe 11 patients with a new syndrome that we term scalp dysesthesia. Of 11 patients, 9 benefited from treatment with low doses of antidepressants.
皮肤感觉异常综合征是一种以慢性皮肤症状为特征但无客观检查发现的疾病。患者主诉灼痛、刺痛或瘙痒,这些症状常由心理或身体压力引发或加重。这些症状可能是潜在精神障碍的表现,也可能代表一种慢性疼痛综合征。
11名女性仅表现为头皮慢性剧痛和/或瘙痒,无客观体征,我们将这种情况称为“头皮感觉异常”。5名女性仅描述有疼痛、刺痛或灼痛;4名女性主诉疼痛和瘙痒;2名女性仅报告有瘙痒。患者年龄在36至70岁之间。症状持续时间从9个月至7年不等。5名女性被医生诊断患有精神障碍,包括心境恶劣障碍、广泛性焦虑和躯体化障碍。7名女性报告压力会引发或加重她们的症状。8名女性使用低剂量盐酸多塞平或盐酸阿米替林治疗后症状改善或完全缓解。1名患者使用舍曲林和盐酸羟嗪治疗后完全缓解,但随后复发。
我们描述了11例患有一种我们称为头皮感觉异常的新综合征的患者。11例患者中,9例从低剂量抗抑郁药治疗中获益。