Gupta A S, Heinzman S, Levine E A
Department of Surgery, Louisiana State University and the Stanley S. Scott Cancer Center, New Orleans 70112, USA.
South Med J. 1998 Mar;91(3):289-92. doi: 10.1097/00007611-199803000-00018.
Merkel's cell carcinoma is an uncommon neuroendocrine cutaneous neoplasm. An unusual mode of dissemination of this tumor is the phenomenon of in-transit metastases. We report complete resolution of in-transit metastases from a Merkel's cell carcinoma in response to treatment with isolated hyperthermic limb perfusion with melphalan. Limb perfusion appears to be a promising modality for such lesions.
默克尔细胞癌是一种罕见的神经内分泌皮肤肿瘤。这种肿瘤一种不寻常的扩散方式是途中转移现象。我们报告了一例默克尔细胞癌的途中转移灶经美法仑隔离肢体热灌注治疗后完全消退。肢体灌注似乎是治疗此类病变的一种有前景的方法。