Yoshii M, Yanashima K, Nakata Y, Nozawa F, Okisaka S
Department of Ophthalmology, National Defense Medical College, Saitama-ken, Japan.
Ophthalmic Res. 1998;30(2):90-5. doi: 10.1159/000055459.
The receptive field size of retinal ganglion cells is closely related to their eccentricity from the fovea. To elicit larger pattern-reversal electroretinograms (P-ERGs), it may be useful to stimulate the retina with patterns having elements that parallel this change in receptive field size. We describe a dartboard pattern consisting of reversal elements that enlarge gradually from the central to the peripheral stimulus field. The utility of the dartboard pattern for eliciting P-ERG was investigated by comparing it with the conventional uniform checkerboard pattern, but with the other stimulus parameters remaining unchanged (96% contrast, 35.9 cd/m2 mean luminance, 3.3 rev/s temporal frequency, 15 degrees circular field). The dartboard pattern produced a significantly larger P50 amplitude than did the checkerboard pattern, while no difference in peak latency was found when 54 min of arc was used as a standard check size for the checkerboard pattern. The dartboard pattern for eliciting P-ERG should prove clinically useful.
视网膜神经节细胞的感受野大小与其离中央凹的偏心度密切相关。为了引出更大的图形翻转视网膜电图（P-ERG），用具有与感受野大小变化平行的元素的图形刺激视网膜可能会有用。我们描述了一种飞镖靶图形，它由从中央刺激区域到周边刺激区域逐渐增大的翻转元素组成。通过将飞镖靶图形与传统的均匀棋盘格图形进行比较，在其他刺激参数保持不变（96%对比度、35.9 cd/m²平均亮度、3.3转/秒时间频率、15度圆形视野）的情况下，研究了飞镖靶图形引出P-ERG的效用。飞镖靶图形产生的P50振幅明显大于棋盘格图形，而当将54分视角用作棋盘格图形的标准方格大小时，未发现峰值潜伏期有差异。用于引出P-ERG的飞镖靶图形在临床上应该会很有用。
