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Reaction of acyl glucuronides with insulin in vitro: identification of an imine mechanism by electrospray ionization mass spectrometry.

作者信息

Liu J H, Marquez C D, Weintraub S T, Smith P C

机构信息

School of Pharmacy, University of North Carolina at Chapel Hill 27599, USA.

出版信息

Pharm Res. 1998 Feb;15(2):343-6. doi: 10.1023/a:1011995408539.

DOI:10.1023/a:1011995408539
PMID:9523325
Abstract
摘要

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本文引用的文献

1
Influence of renal failure in rats on the disposition of salicyl acyl glucuronide and covalent binding of salicylate to plasma proteins.
J Pharmacol Exp Ther. 1996 Jul;278(1):277-83.
2
Evidence for covalent binding of acyl glucuronides to serum albumin via an imine mechanism as revealed by tandem mass spectrometry.串联质谱法揭示酰基葡萄糖醛酸通过亚胺机制与血清白蛋白共价结合的证据。
Proc Natl Acad Sci U S A. 1993 May 1;90(9):3797-801. doi: 10.1073/pnas.90.9.3797.
3
Covalent binding of suprofen acyl glucuronide to albumin in vitro.
Xenobiotica. 1993 Apr;23(4):337-48. doi: 10.3109/00498259309057022.
4
Reactivity of tolmetin glucuronide with human serum albumin. Identification of binding sites and mechanisms of reaction by tandem mass spectrometry.托美汀葡糖醛酸与人类血清白蛋白的反应活性。通过串联质谱法鉴定结合位点及反应机制。
Drug Metab Dispos. 1995 Mar;23(3):369-76.
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Sites of nonenzymatic glycosylation of human hemoglobin A.人血红蛋白A的非酶糖基化位点。
J Biol Chem. 1980 Apr 10;255(7):3120-7.
6
Properties of acyl glucuronides: implications for studies of the pharmacokinetics and metabolism of acidic drugs.酰基葡萄糖醛酸苷的性质：对酸性药物药代动力学和代谢研究的启示
Drug Metab Rev. 1984;15(5-6):1213-49. doi: 10.3109/03602538409033562.
7
Irreversible binding of zomepirac to plasma protein in vitro and in vivo.佐美酸在体外和体内与血浆蛋白的不可逆结合。
J Clin Invest. 1986 Mar;77(3):934-9. doi: 10.1172/JCI112392.
8
Reactions of oxaprozin-1-O-acyl glucuronide in solutions of human plasma and albumin.
Adv Exp Med Biol. 1986;197:431-41. doi: 10.1007/978-1-4684-5134-4_42.
9
Reaction of bilirubin glucuronides with serum albumin.
J Chromatogr. 1986 Dec 19;383(2):387-92. doi: 10.1016/s0378-4347(00)83484-2.
10
Effect of pH on acyl migration and hydrolysis of tolmetin glucuronide.
Drug Metab Dispos. 1988 Mar-Apr;16(2):322-4.