[体育锻炼对慢性心肌梗死患者脂质代谢参数的作用]

[The role of physical training in lipid metabolic parameters in patients with chronic myocardial infarct].

作者信息

Mitu F, Azoicăi D, Gheorghiţă N

机构信息

Clinica Medicală Recuperare, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.

出版信息

Rev Med Chir Soc Med Nat Iasi. 1995 Jan-Jun;99(1-2):63-71.

PMID:9524658

Abstract

OBJECTIVES

The aim of the study is to follow the variation of some parameters of the lipidic metabolism, during physical training, at patients with chronic myocardial infarction.

METHODS

Among 132 patients with chronic myocardial infarction, we selected 22 patients, mean age 47.4 +/- 6.08 years from which 18 followed supervised physical training a period of 3-6 months. There were determined before and at the end of the interval, the following parameters: serum lipids, serum cholesterol, HDLcol, LDLcol, triglicerids, apolipoproteins A,B, Apo B/A ratio. The statistical comparison has been made for each parameters, by univariate and multivariate analysis.

RESULTS

HDLcol increased significantly in the study group at the end of the interval (from 28.9 mg% to 42.3 mg%, p < 0.001); LDLcol and total cholesterol did not vary. Apo A increased significantly, but Apo B/A ratio did not change.

CONCLUSIONS

Physical training altered the lipidic profile by increasing the protective fraction of the cholesterol--HDLcol and Apo A.

摘要

目的

本研究旨在追踪慢性心肌梗死患者在体育锻炼期间脂质代谢某些参数的变化。

方法

在132例慢性心肌梗死患者中，我们选取了22例平均年龄为47.4±6.08岁的患者，其中18例接受了为期3至6个月的有监督体育锻炼。在该时间段开始前和结束时测定了以下参数：血脂、血清胆固醇、高密度脂蛋白胆固醇（HDLcol）、低密度脂蛋白胆固醇（LDLcol）、甘油三酯、载脂蛋白A、B、载脂蛋白B/A比值。通过单变量和多变量分析对每个参数进行了统计学比较。