Dent C E, Faccini J, Hodsman A
Arch Dis Child. 1976 Mar;51(3):223-6. doi: 10.1136/adc.51.3.223.
A healthy girl of 10 years presented with lumps on her tongue, shown on biopsy to be neuromas. She had had operations to her feet for pes cavus and was relatively long-limbed but had no other 'Marfanoid' features. She had a high plasma calcitonin level. At operation a normal sized thyroid gland was totally removed. It contained two discrete masses of malignant C-cells and diffuse foci elsewhere. The plasma calcitonin fell slowly to normal on follow-up but was noted to be rising 2 1/2 years later. We stress the importance of making this diagnosis as early as possible and mention briefly another child aged 15 months, similarly diagnosed and operated upon.
一名10岁健康女孩因舌部出现肿块就诊，活检显示为神经瘤。她曾因高弓足接受过足部手术，四肢相对较长，但无其他“马方综合征样”特征。她的血浆降钙素水平较高。手术中完整切除了大小正常的甲状腺。甲状腺内有两个离散的恶性C细胞团块，其他部位有弥漫性病灶。随访期间血浆降钙素缓慢降至正常，但在2年半后发现又开始上升。我们强调尽早做出该诊断的重要性，并简要提及另一名15个月大的儿童，其诊断和手术情况与此相似。
