外周骨化性纤维瘤和骨化性纤维瘤中的增殖活性。

Proliferative activity in peripheral ossifying fibroma and ossifying fibroma.

作者信息

Mesquita R A, Orsini S C, Sousa M, de Araújo N S

机构信息

Department of Oral Pathology, School of Dentistry, University of Minas Gerais, Brazil.

出版信息

J Oral Pathol Med. 1998 Feb;27(2):64-7. doi: 10.1111/j.1600-0714.1998.tb02095.x.

DOI:10.1111/j.1600-0714.1998.tb02095.x

PMID:9526731

Abstract

A proliferative activity study analysing morphometric and quantitative aspects of nucleolar organizer regions (NORs) and proliferating cell nuclear antigen (PCNA) expression was conducted in 10 cases of peripheral ossifying fibroma (POF) and 10 cases of ossifying fibroma (OF). For NOR identification, the silver staining technique (AgNOR technique) was used. PCNA expression was determined by immunohistochemical staining using the PC10 antibody. The AgNOR analysis for the two lesions showed a profile characteristic of benign lesions. OF showed higher AgNOR number and PCNA expression than POF. Our results suggest increased proliferative activity in OF compared with POF.

摘要

对10例外周骨化性纤维瘤（POF）和10例骨化性纤维瘤（OF）进行了一项增殖活性研究，分析核仁组织区（NORs）的形态计量学和定量方面以及增殖细胞核抗原（PCNA）的表达。为了鉴定NOR，使用了银染色技术（AgNOR技术）。通过使用PC10抗体的免疫组织化学染色来确定PCNA的表达。对这两种病变的AgNOR分析显示出良性病变的特征。与POF相比，OF显示出更高的AgNOR数量和PCNA表达。我们的结果表明，与POF相比，OF的增殖活性增加。