Ileri M, Büyükaşik Y, Ileri N S, Haznedaroglu I C, Göksel S, Kirazli S, Dündar S
Department of Hematology, Hacettepe University Medical School, Ankara, Turkey.
Am J Cardiol. 1998 Mar 15;81(6):795-7. doi: 10.1016/s0002-9149(97)01025-4.
The aim of this study was to assess whether there is blood coagulation activation in patients with mitral stenosis (MS) and sinus rhythm (SR) and to investigate the value of left atrial spontaneous echo contrast (LASEC) as a predictive sign of increased coagulation activity. Using thrombin-antithrombin III complexes and prothrombin fragment 1+2 as in vivo hemostatic markers, we concluded that there is a hypercoagulable state in patients with MS and SR when LASEC is present.
本研究的目的是评估二尖瓣狭窄（MS）和窦性心律（SR）患者是否存在凝血激活，并探讨左心房自发显影（LASEC）作为凝血活性增加预测指标的价值。使用凝血酶 - 抗凝血酶III复合物和凝血酶原片段1 + 2作为体内止血标志物，我们得出结论，当存在LASEC时，MS和SR患者存在高凝状态。
