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631例宫颈浸润癌患者的治疗与生存情况

Treatment and survival in 631 patients with invasive carcinoma of the cervix.

作者信息

Gad C

出版信息

Br J Obstet Gynaecol. 1976 Jul;83(7):560-6. doi: 10.1111/j.1471-0528.1976.tb00886.x.

DOI:10.1111/j.1471-0528.1976.tb00886.x
PMID:952785
Abstract

From 1951 to 1972, a total of 631 cases of invasive carcinoma of the cervix were diagnosed in Frederiksberg, Copenhagen, Denmark. Treatment was either by surgery or radiotherapy, a combination of both being rarely used. The crude five-year survival rates were 99 per cent in stage Ia, 79 per cent in stage Ib, 67 per cent in stage IIa, 45 per cent in stage IIb, 23 per cent in stage III, 5 per cent in stage IV and 63 per cent for all stages. The relative survival rates were respectively 100 per cent, 81 per cent, 73 per cent, 48 per cent, 26 per cent, 5 per cent and 66 per cent. Radical hysterectomy were found more effective than radiotherapy in stage Ib carcinoma of the cervix. This difference was not explained by age but other factors possibly playing a role are considered. The combination of surgery and radiotherapy is discussed and only seems indicated for patients with stage Ib carcinoma and lymph node metastases.

摘要

1951年至1972年期间,丹麦哥本哈根腓特烈斯贝共诊断出631例宫颈浸润癌病例。治疗方法为手术或放疗,很少使用两者结合的方式。Ia期的粗五年生存率为99%,Ib期为79%,IIa期为67%,IIb期为45%,III期为23%,IV期为5%,所有阶段综合为63%。相对生存率分别为100%、81%、73%、48%、26%、5%和66%。在Ib期宫颈癌中,根治性子宫切除术比放疗更有效。这种差异并非由年龄所致,但考虑到可能起作用的其他因素。文中讨论了手术与放疗相结合的方法,似乎仅适用于Ib期癌且有淋巴结转移的患者。

相似文献

1
Treatment and survival in 631 patients with invasive carcinoma of the cervix.631例宫颈浸润癌患者的治疗与生存情况
Br J Obstet Gynaecol. 1976 Jul;83(7):560-6. doi: 10.1111/j.1471-0528.1976.tb00886.x.
2
Irradiation alone or combined with surgery in stage IB, IIA, and IIB carcinoma of uterine cervix: update of a nonrandomized comparison.子宫颈癌IB期、IIA期和IIB期单纯放疗或放疗联合手术:非随机对照研究的更新
Int J Radiat Oncol Biol Phys. 1995 Feb 15;31(4):703-16. doi: 10.1016/0360-3016(94)00523-0.
3
Lack of effect of tumor size on the prognosis of carcinoma of the uterine cervix Stage IB and IIA treated with preoperative irradiation and surgery.肿瘤大小对术前放疗及手术治疗的子宫颈癌IB期和IIA期预后无影响。
Int J Radiat Oncol Biol Phys. 1999 Oct 1;45(3):645-51. doi: 10.1016/s0360-3016(99)00217-5.
4
Radical hysterectomy in the treatment of cervical cancer.根治性子宫切除术治疗宫颈癌。
Am J Obstet Gynecol. 1980 May 15;137(2):254-62. doi: 10.1016/0002-9378(80)90782-6.
5
Radiation therapy alone or combined with surgery in the treatment of barrel-shaped carcinoma of the uterine cervix (stages IB, IIA, IIB).单独放射治疗或联合手术治疗子宫颈桶状癌(IB期、IIA期、IIB期)。
Int J Radiat Oncol Biol Phys. 1985 Nov;11(11):1903-9. doi: 10.1016/0360-3016(85)90270-6.
6
[Analysis of lymph node status and lymph node morphology in cervix cancer operated by the Wertheim-Meigs-Okabayashi method].[对采用韦特海姆-梅格斯-冈林法手术的宫颈癌患者淋巴结状态及淋巴结形态的分析]
Zentralbl Gynakol. 1992;114(3):122-6.
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Carcinoma of the uterine cervix. I. Impact of prolongation of overall treatment time and timing of brachytherapy on outcome of radiation therapy.子宫颈癌。I. 总治疗时间延长及近距离放疗时机对放射治疗结局的影响。
Int J Radiat Oncol Biol Phys. 1995 Jul 30;32(5):1275-88. doi: 10.1016/0360-3016(95)00220-S.
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[The histologically evaluated accuracy of lymphography in operative therapy of invasive cervix cancer stages Ib-IIb].[组织学评估淋巴造影术在浸润性宫颈癌Ib-IIb期手术治疗中的准确性]
Zentralbl Gynakol. 1985;107(12):721-5.
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[Radical hysterectomy with pelvic lymphadenectomy in patients with carcinoma of the uterine cervix--3 years' experience].[子宫颈癌患者行根治性子宫切除术及盆腔淋巴结清扫术——3年经验]
Srp Arh Celok Lek. 1998 May-Jun;126(5-6):183-7.
10
Survival of women with microinvasive adenocarcinoma of the cervix is not improved by radical surgery.根治性手术并不能提高宫颈微浸润腺癌女性患者的生存率。
Am J Obstet Gynecol. 2017 Sep;217(3):332.e1-332.e6. doi: 10.1016/j.ajog.2017.05.021. Epub 2017 May 15.

引用本文的文献

1
Changes in prevalence and clinical characteristics of cervical cancer in the People's Republic of China: a study of 10,012 cases from a nationwide working group.中国宫颈癌发病率和临床特征的变化:全国工作组 10012 例病例研究。
Oncologist. 2013;18(10):1101-7. doi: 10.1634/theoncologist.2013-0123. Epub 2013 Sep 16.
2
Hematometra complicating hormone replacement therapy after radiation for cervical carcinoma.宫颈癌放疗后激素替代治疗并发子宫积血。
Arch Gynecol Obstet. 1988;243(4):235-6. doi: 10.1007/BF00932274.