视网膜母细胞瘤肿瘤中的突触形成。
Synapse formation in retinoblastoma tumours.
作者信息
Dickson D H, Ramsey M S, Tonus J G
出版信息
Br J Ophthalmol. 1976 May;60(5):371-5. doi: 10.1136/bjo.60.5.371.
Abstract
Developing photoreceptor-like cells in retinoblastoma tumour fleurettes were found to contain apical tight junctions, mitochondrial-filled inner segment regions with cilia, and basally located synaptic ribbons and vesicles. Synaptic contract appeared to be established with adjacent neuronal-like elements. We suggest that photoreceptor differentiation in retinoblastoma tumours follows a sequence similar to normal human photoreceptor embryogenesis.
摘要
在视网膜母细胞瘤小花中发现的发育中的光感受器样细胞含有顶端紧密连接、带有纤毛的充满线粒体的内段区域，以及位于基部的突触带和小泡。突触连接似乎是与相邻的神经元样元件建立的。我们认为视网膜母细胞瘤中的光感受器分化遵循与正常人光感受器胚胎发生相似的序列。
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