Ruben M, Brown N, Lobascher D, Chaston J, Morris J
Br J Ophthalmol. 1976 Jul;60(7):529-31. doi: 10.1136/bjo.60.7.529.
The study of 151 patients wearing soft hydrophilic lenses for one year revealed no gross irreversible lesions with loss of vision. But of significance was the presence of superficial lesions of the corneal epithelium, and chronic stromal oedema. While no significant loss of wearing time was noted for women taking the pill, the decrease in tear secretion in those patients with a latent dry eye problem could just alter the balance to produce intolerance. From this report it is the long-term changes to the tissues that remain to be fully investigated for soft hydrophilic lenses.
对151名佩戴软性亲水镜片一年的患者进行的研究表明，未发现导致视力丧失的严重不可逆病变。但具有重要意义的是存在角膜上皮浅表病变和慢性基质水肿。虽然服用避孕药的女性佩戴时间没有明显减少，但那些有潜在干眼问题的患者泪液分泌减少可能会改变平衡从而导致不耐受。从这份报告来看，软性亲水镜片对组织的长期影响仍有待充分研究。
