Franco M, Paniagua R, Herrera-Acosta J
Department of Nephrology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Curr Opin Nephrol Hypertens. 1998 Mar;7(2):153-8. doi: 10.1097/00041552-199803000-00003.
Pharmacological interruption of the renin-angiotensin system at different pathway levels has extended our knowledge on the distribution of angiotensin receptors in different nephron segments, its regulation and tubular cell responses. Novel beneficial effects obtained with blockade of this peptide on cellular proliferation and its interaction with other vasoactive systems are particularly important for preventing renal damage.
在不同途径水平对肾素-血管紧张素系统进行药理学阻断，扩展了我们对血管紧张素受体在不同肾单位节段的分布、其调节以及肾小管细胞反应的认识。通过阻断该肽所获得的关于细胞增殖及其与其他血管活性系统相互作用的新的有益作用，对于预防肾损伤尤为重要。
