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恶疫霉对Δ7-和Δ5,7-甾醇的代谢

Metabolism of delta7- and delta5,7-sterols by Phytophthora cactorum.

作者信息

Knights B A, Elliott C G

出版信息

Biochim Biophys Acta. 1976 Aug 23;441(2):341-6. doi: 10.1016/0005-2760(76)90178-8.

DOI:10.1016/0005-2760(76)90178-8
PMID:952995
Abstract

delta7- and delta5,7-Sterols are converted to the corresponding delta5-sterols by Phytophthora cactorum. When delta7-sterols were supplied to the fungus, delta5- and delta7-sterols were recovered in an acetone extract of the mycelium, the proportion of delta5-sterol being higher in the free sterol fraction than in the esters. When delta5,7-sterols were supplied, delta5-sterols were recovered. No delta5,7-sterols were found in the mycelium. The initial rate of uptake of the sterols was in the order delta5 greater than delta7 greater than delta5,7.

摘要

δ7-甾醇和δ5,7-甾醇被恶疫霉转化为相应的δ5-甾醇。当向该真菌提供δ7-甾醇时,在菌丝体的丙酮提取物中回收了δ5-甾醇和δ7-甾醇,游离甾醇部分中δ5-甾醇的比例高于酯类中的比例。当提供δ5,7-甾醇时,回收了δ5-甾醇。在菌丝体中未发现δ5,7-甾醇。甾醇的初始摄取速率顺序为δ5>δ7>δ5,7。

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