Eckstein F, Tieschky M, Faber S C, Haubner M, Kolem H, Englmeier K H, Reiser M
Institute for Diagnostic Radiology, Klinikum Grosshadern, Munich, Germany.
Radiology. 1998 Apr;207(1):243-8. doi: 10.1148/radiology.207.1.9530322.
To quantify, with magnetic resonance (MR) imaging, the in vivo changes in cartilage volume and thickness after physical exercise.
The patellae of eight volunteers were imaged six times at physical test by using a spoiled fat-suppressed gradient-echo sequence with an acquisition time of 4.10 minutes. The volunteers then performed 50 knee bends, and two more data sets were acquired 3-7 minutes and 8-12 minutes after exercise. The patellar cartilage volume was determined after three-dimensional reconstruction, and the thickness was assessed with a three-dimensional minimal-distance algorithm.
Whereas repositioning had a small effect on the measurements (mean coefficient of variation, 1.4%), a statistically significant decrease in cartilage volume was observed 3-7 minutes (mean decrease, 6.0%; P < .05) and 8-12 minutes (mean decrease, 5.2%; P < .05) after exercise. The deformation was homogeneous throughout the joint surface. In one asymptomatic volunteer, a cartilage lesion became more pronounced after exercise.
MR imaging can be used to investigate the response of articular cartilage to physical exercise in vivo. Patients or volunteers should be allowed a sufficient period of physical rest if quantitative measurements of cartilage volume and thickness are to be undertaken in longitudinal studies.
利用磁共振成像（MR）对体育锻炼后体内软骨体积和厚度的变化进行量化。
8名志愿者的髌骨在体能测试时使用破坏式脂肪抑制梯度回波序列成像6次，采集时间为4.10分钟。志愿者随后进行50次屈膝动作，并在运动后3 - 7分钟和8 - 12分钟采集另外两组数据集。三维重建后确定髌软骨体积，并用三维最小距离算法评估厚度。
尽管重新定位对测量结果影响较小（平均变异系数为1.4%），但运动后3 - 7分钟（平均减少6.0%；P < 0.05）和8 - 12分钟（平均减少5.2%；P < 0.05）观察到软骨体积有统计学意义的减少。整个关节表面的变形是均匀的。在一名无症状志愿者中，运动后软骨损伤变得更加明显。
MR成像可用于研究体内关节软骨对体育锻炼的反应。如果要在纵向研究中对软骨体积和厚度进行定量测量，患者或志愿者应给予足够的体力休息时间。
