Salchow D J, Zirm M E, Stieldorf C, Parisi A
J Cataract Refract Surg. 1998 Feb;24(2):175-82. doi: 10.1016/s0886-3350(98)80197-1.
To evaluate the precision and safety of myopia and astigmatism correction using laser in situ keratomileusis (LASIK).
Augenchirurgie und Laserzentrum Hoch-Rum (Sanatorium der Kreuzsch-western), Innsbruck, Austria.
In this prospective study, LASIK was performed on 66 eyes of 39 patients with myopia ranging from 1.50 to 16.00 diopters (D). Astigmatism, ranging from -0.00 to -3.00 D, was treated simultaneously. Surgery was performed with the Chiron Keracor 117 excimer laser and the Chiron Automated Corneal Shaper microkeratome. During the 6 month follow-up, manifest refraction as well as best corrected and uncorrected visual acuities were measured; corneal topographies were produced and slitlamp biomicroscopy was performed. Changes in visual acuity and corneal topography were evaluated.
After 6 months, mean myopia had decreased from 6.78 D +/- 3.48 (SD) to 0.40 +/- 0.98 D. Fifty-one of 63 eyes (81.0%) were within +/- 1.00 D of spherical emmetropia and 61 of 63 (96.8%) within +/- 1.00 D of cylindrical emmetropia. Uncorrected visual acuity improved in all eyes; it was 20/40 or better in 82.5% 6 months postoperatively. Best corrected visual acuity did not change in most eyes; 9.5% lost two or more Snellen lines. No central islands or corneal scars were detected postoperatively. Haze was noted in only 6 eyes (9.1%); it was transient and less than grade 1. No sight-threatening complications occurred intraoperatively.
Laser in situ keratomileusis was an exact and predictable procedure for correcting low, moderate, and high myopia and myopic astigmatism.
评估准分子原位角膜磨镶术（LASIK）矫正近视和散光的准确性及安全性。
奥地利因斯布鲁克市的奥根眼科及激光中心Hoch-Rum（十字西部疗养院）。
在这项前瞻性研究中，对39例近视度数在1.50至16.00屈光度（D）之间的患者的66只眼实施了LASIK手术。同时治疗了散光度数在-0.00至-3.00 D之间的患者。手术采用Chiron Keracor 117准分子激光和Chiron自动角膜板层刀进行。在6个月的随访期间，测量了显验光、最佳矫正视力和未矫正视力；进行了角膜地形图检查和裂隙灯显微镜检查。评估了视力和角膜地形图的变化。
6个月后，平均近视度数从6.78 D±3.48（标准差）降至0.40±0.98 D。63只眼中有51只眼（81.0%）的球镜度数在±1.00 D范围内达到球镜正视化，63只眼中有61只眼（96.8%）的柱镜度数在±1.00 D范围内达到柱镜正视化。所有眼睛的未矫正视力均有提高；术后6个月时，82.5%的眼睛视力达到20/40或更好。大多数眼睛的最佳矫正视力未改变；9.5%的眼睛视力下降了两行或更多。术后未发现中央岛或角膜瘢痕。仅6只眼（9.1%）出现了角膜雾状混浊；为一过性，且低于1级。术中未发生威胁视力的并发症。
准分子原位角膜磨镶术是一种精确且可预测的手术方法，可用于矫正低、中、高度近视及近视散光。
