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硅胶碎屑颗粒所致腕关节滑膜炎的治疗结果

The results of treatment of synovitis of the wrist induced by particles of silicone debris.

作者信息

Murray P M, Wood M B

机构信息

Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.

出版信息

J Bone Joint Surg Am. 1998 Mar;80(3):397-406.

PMID:9531208
Abstract

Synovitis of the wrist induced by particles of silicone debris is a destructive inflammatory process. Many silicone-rubber carpal implants remain in place, and there are few reports regarding the treatment of this condition. The purpose of the present study was to examine the results of treatment of synovitis induced by particles of silicone debris. Twenty-eight patients were identified, with use of computerized indexing, as having been evaluated for silicone-induced synovitis between 1972 and 1992. Seventeen of the twenty-eight patients were included in the study. At the time of the latest follow-up, twelve of the seventeen patients had pain, thirteen of the fourteen patients for whom radiographs were available had evidence of osteolysis typical of that associated with debris-induced synovitis, and eight of the seventeen patients reported difficulty with activities of daily living because of problems with the wrist. Seven patients had been treated non-operatively, and ten had been treated operatively. With the small number of patients available for study, we could not detect a significant difference between the two groups with respect to pain, perceived limitation of motion, difficulty with activities of daily living, grip strength, or the total range of motion of the wrist. There was no significant difference between the two groups with regard to the age at the time of the initial procedure, the time to the diagnosis of the synovitis, and the duration of follow-up after treatment. There was no clear advantage to removal of the implant and débridement with or without arthrodesis of the wrist or other reconstructive procedures. We recommend caution when a reconstructive or salvage procedure in the wrist is selected for a patient who has synovitis induced by particles of silicone debris.

摘要

硅酮碎屑颗粒所致的腕关节滑膜炎是一种破坏性炎症过程。许多硅橡胶腕部植入物仍留在原位,而关于这种病症治疗的报道较少。本研究的目的是探讨硅酮碎屑颗粒所致滑膜炎的治疗结果。通过计算机检索,确定28例患者在1972年至1992年间曾接受过硅酮诱导滑膜炎的评估。28例患者中有17例纳入研究。在最近一次随访时,17例患者中有12例有疼痛,在有X线片的14例患者中,13例有与碎屑诱导滑膜炎相关的典型骨质溶解证据,17例患者中有8例因腕部问题报告日常生活活动有困难。7例患者接受了非手术治疗,10例接受了手术治疗。由于可供研究的患者数量较少,我们未能在两组之间发现疼痛、感觉运动受限、日常生活活动困难、握力或腕关节总活动范围方面的显著差异。两组在初次手术时的年龄、滑膜炎诊断时间以及治疗后的随访时间方面无显著差异。无论是否进行腕关节融合或其他重建手术,取出植入物并进行清创术并无明显优势。对于患有硅酮碎屑颗粒所致滑膜炎的患者,在选择腕关节重建或挽救手术时,我们建议谨慎行事。

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