Hansen P O, Svensson P, Nielsen J, Arendt-Nielsen L, Jensen T S
Danish Pain Research Center and Dept of Neurology, Aarhus University Hospital.
Acta Neurol Scand. 1998 Mar;97(3):204-13. doi: 10.1111/j.1600-0404.1998.tb00638.x.
The late exteroceptive suppression period (ES2) of the masseter muscle is conventionally quantified by a combination of measures of duration, amplitude, or mean activity. The combination of measures makes it difficult to compare ES2s obtained from different set-ups. An unbiased method for quantitating ES2 is introduced allowing ranking of ES2s. The introduced method is utilized to evaluate stimulus and recording conditions under which ES2 is maximal.
Fifteen male volunteers participated in 3 experiments designed to determine the effect of level of teeth clenching, stimulus intensity, and perceived pain intensity on the ES2.
Coefficients of variance (1 h/1 month) were: duration: 11%/43%, latency: 9%/12%, and magnitude of suppression: 11%/12%. A level of teeth clenching of 66% of maximal voluntary bite force, and a stimulus intensity below pain detection threshold was associated with maximal magnitude of suppression of ES2.
The introduced method is reproducible and allows ranking and stimulus-response estimations of ES2. It is suggested that ES2 does not reflect activity along the nociceptive pathways in the trigeminal region.
咬肌的晚期外感受性抑制期（ES2）传统上通过持续时间、幅度或平均活动度等指标的组合来量化。这些指标的组合使得比较不同设置下获得的ES2变得困难。本文介绍了一种无偏量化ES2的方法，可对ES2进行排序。该方法用于评估ES2最大时的刺激和记录条件。
15名男性志愿者参与了3项实验，旨在确定咬牙程度、刺激强度和疼痛感知强度对ES2的影响。
方差系数（1小时/1个月）分别为：持续时间：11%/43%，潜伏期：9%/12%，抑制幅度：11%/12%。最大自主咬合力的66%的咬牙程度以及低于疼痛检测阈值的刺激强度与ES2的最大抑制幅度相关。
所介绍的方法具有可重复性，能够对ES2进行排序并进行刺激-反应估计。研究表明，ES2并不反映三叉神经区域伤害性感受通路的活动。
