连续123例患者接受不进行抗淋巴细胞诱导治疗的他克莫司治疗，可预防胰腺因排斥反应而丢失。

Tacrolimus without antilymphocyte induction therapy prevents pancreas loss from rejection in 123 consecutive patients.

作者信息

Corry R J, Egidi M F, Shapiro R, Sugitani A, Gritsch H A, Jordan M L, Dodson S F, Vivas C A, Scantlebury V P, Rao A S, Fung J J, Starzl T E

机构信息

Starzl Transplantation Institute, University of Pittsburgh, Pennsylvania, USA.

出版信息

Transplant Proc. 1998 Mar;30(2):521. doi: 10.1016/s0041-1345(97)01385-7.

DOI:10.1016/s0041-1345(97)01385-7

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2977929/

Abstract

In this series, antilymphoid induction therapy did not appear to be necessary to prevent early graft loss from rejection. In addition, we have followed cytomegalovirus (CMV) antigenemia (pp65) for CMV infection. Although some patients developed a positive antigenemia in the seropositive to negative donor-recipient combinations, only one patient had a prolonged febrile course for 1 week.

摘要

在本系列研究中，抗淋巴细胞诱导治疗似乎并非预防移植早期因排斥反应而丢失所必需的。此外，我们对巨细胞病毒（CMV）感染进行了CMV抗原血症（pp65）监测。尽管在供体血清学阳性而受体血清学阴性的组合中，一些患者出现了抗原血症阳性，但只有一名患者出现了持续1周的发热病程。

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Tacrolimus without antilymphocyte induction therapy prevents pancreas loss from rejection in 123 consecutive patients.连续123例患者接受不进行抗淋巴细胞诱导治疗的他克莫司治疗，可预防胰腺因排斥反应而丢失。

Transplant Proc. 1998 Mar;30(2):521. doi: 10.1016/s0041-1345(97)01385-7.

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Tacrolimus in pancreas transplantation: a multicenter analysis. Tacrolimus Pancreas Transplant Study Group.他克莫司在胰腺移植中的应用：一项多中心分析。他克莫司胰腺移植研究组。

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The use of intravenous tacrolimus and mycophenolate mofetil as induction and maintenance immunosuppression in simultaneous pancreas--kidney recipients with previous transplants.静脉注射他克莫司和霉酚酸酯在有既往移植史的胰肾联合移植受者中作为诱导和维持免疫抑制治疗的应用。

Clin Transplant. 2001 Apr;15(2):142-5. doi: 10.1034/j.1399-0012.2001.150211.x.

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Long-term results of pancreas transplantation under tacrolius immunosuppression.他克莫司免疫抑制下胰腺移植的长期结果。

Transplantation. 1999 Jan 27;67(2):266-72. doi: 10.1097/00007890-199901270-00014.

本文引用的文献

1

Pancreas transplantation with enteric drainage under tacrolimus induction therapy.在他克莫司诱导治疗下进行胰肠引流式胰腺移植。

Transplant Proc. 1997 Feb-Mar;29(1-2):642. doi: 10.1016/s0041-1345(96)00375-2.

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