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连续123例患者接受不进行抗淋巴细胞诱导治疗的他克莫司治疗,可预防胰腺因排斥反应而丢失。

Tacrolimus without antilymphocyte induction therapy prevents pancreas loss from rejection in 123 consecutive patients.

作者信息

Corry R J, Egidi M F, Shapiro R, Sugitani A, Gritsch H A, Jordan M L, Dodson S F, Vivas C A, Scantlebury V P, Rao A S, Fung J J, Starzl T E

机构信息

Starzl Transplantation Institute, University of Pittsburgh, Pennsylvania, USA.

出版信息

Transplant Proc. 1998 Mar;30(2):521. doi: 10.1016/s0041-1345(97)01385-7.

DOI:10.1016/s0041-1345(97)01385-7
PMID:9532157
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2977929/
Abstract

In this series, antilymphoid induction therapy did not appear to be necessary to prevent early graft loss from rejection. In addition, we have followed cytomegalovirus (CMV) antigenemia (pp65) for CMV infection. Although some patients developed a positive antigenemia in the seropositive to negative donor-recipient combinations, only one patient had a prolonged febrile course for 1 week.

摘要

在本系列研究中,抗淋巴细胞诱导治疗似乎并非预防移植早期因排斥反应而丢失所必需的。此外,我们对巨细胞病毒(CMV)感染进行了CMV抗原血症(pp65)监测。尽管在供体血清学阳性而受体血清学阴性的组合中,一些患者出现了抗原血症阳性,但只有一名患者出现了持续1周的发热病程。

相似文献

1
Tacrolimus without antilymphocyte induction therapy prevents pancreas loss from rejection in 123 consecutive patients.连续123例患者接受不进行抗淋巴细胞诱导治疗的他克莫司治疗,可预防胰腺因排斥反应而丢失。
Transplant Proc. 1998 Mar;30(2):521. doi: 10.1016/s0041-1345(97)01385-7.
2
Benefits and risks of early antilymphocyte rescue in simultaneous kidney-pancreas transplant recipients.同期肾胰联合移植受者早期抗淋巴细胞挽救治疗的获益与风险
Transplant Proc. 1998 Mar;30(2):525. doi: 10.1016/s0041-1345(97)01388-2.
3
Tacrolimus eliminates acute rejection as a major complication following simultaneous kidney and pancreas transplantation.他克莫司可消除肾胰联合移植后作为主要并发症的急性排斥反应。
Transplant Proc. 1998 Mar;30(2):509-11. doi: 10.1016/s0041-1345(97)01379-1.
4
Pancreas transplantation without antibody therapy.未进行抗体治疗的胰腺移植
Transplant Proc. 1998 Mar;30(2):299-300. doi: 10.1016/s0041-1345(97)01415-2.
5
Effects of tacrolimus, mycophenolate mofetil, and cyclosporine microemulsion on rejection incidence in synchronous pancreas-kidney transplantation.
Transplant Proc. 1998 Mar;30(2):507-8. doi: 10.1016/s0041-1345(97)01378-x.
6
First results with a quadruple therapy regimen including tacrolimus and mycophenolate mofetil in patients after combined pancreas and kidney transplantation.
Transplant Proc. 1998 Mar;30(2):505-6. doi: 10.1016/s0041-1345(97)01377-8.
7
Tacrolimus in pancreas transplantation: a multicenter analysis. Tacrolimus Pancreas Transplant Study Group.他克莫司在胰腺移植中的应用:一项多中心分析。他克莫司胰腺移植研究组。
Clin Transplant. 1997 Aug;11(4):299-312.
8
Mycophenolate mofetil and tacrolimus for induction and maintenance therapy after pancreas transplantation.霉酚酸酯和他克莫司用于胰腺移植后的诱导和维持治疗。
Transplant Proc. 1998 Mar;30(2):518-20. doi: 10.1016/s0041-1345(97)01384-5.
9
Simultaneous kidney-pancreas transplantation without antilymphocyte induction.不进行抗淋巴细胞诱导的同期肾胰联合移植。
Transplantation. 2000 Jan 15;69(1):49-54. doi: 10.1097/00007890-200001150-00010.
10
The use of intravenous tacrolimus and mycophenolate mofetil as induction and maintenance immunosuppression in simultaneous pancreas--kidney recipients with previous transplants.静脉注射他克莫司和霉酚酸酯在有既往移植史的胰肾联合移植受者中作为诱导和维持免疫抑制治疗的应用。
Clin Transplant. 2001 Apr;15(2):142-5. doi: 10.1034/j.1399-0012.2001.150211.x.

引用本文的文献

1
Long-term results of pancreas transplantation under tacrolius immunosuppression.他克莫司免疫抑制下胰腺移植的长期结果。
Transplantation. 1999 Jan 27;67(2):266-72. doi: 10.1097/00007890-199901270-00014.

本文引用的文献

1
Pancreas transplantation with enteric drainage under tacrolimus induction therapy.在他克莫司诱导治疗下进行胰肠引流式胰腺移植。
Transplant Proc. 1997 Feb-Mar;29(1-2):642. doi: 10.1016/s0041-1345(96)00375-2.