胰岛以及多种细胞系上Fas配体的表达会导致嗜中性粒细胞加速排斥反应。 - Suppr

Suppr

超能文献

Fas ligand expression on islets as well as multiple cell lines results in accelerated neutrophilic rejection.

作者信息

Kang S M, Lin Z, Ascher N L, Stock P G

机构信息

Department of Surgery, University of California at San Francisco, USA.

出版信息

Transplant Proc. 1998 Mar;30(2):538. doi: 10.1016/s0041-1345(97)01396-1.

DOI:10.1016/s0041-1345(97)01396-1

PMID:9532168

Abstract

摘要

相似文献

Fas ligand expression on islets as well as multiple cell lines results in accelerated neutrophilic rejection.胰岛以及多种细胞系上Fas配体的表达会导致嗜中性粒细胞加速排斥反应。

Transplant Proc. 1998 Mar;30(2):538. doi: 10.1016/s0041-1345(97)01396-1.

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction.胰岛中Fas配体的表达不会赋予免疫特权，反而会将胰岛作为快速破坏的靶点。

Nat Med. 1997 Jul;3(7):738-43. doi: 10.1038/nm0797-738.

FasL--too much of a good thing? Transplanted grafts of pancreatic islet cells engineered to express Fas ligand are destroyed not protected by the immune system.FasL——好事过头了？经基因工程改造以表达Fas配体的胰岛细胞移植移植物会被免疫系统破坏而非保护。

Nat Med. 1997 Jul;3(7):727-8. doi: 10.1038/nm0797-727.

A non-cleavable mutant of Fas ligand does not prevent neutrophilic destruction of islet transplants.Fas配体的一种不可裂解突变体不能阻止胰岛移植的嗜中性破坏。

Transplantation. 2000 May 15;69(9):1813-7. doi: 10.1097/00007890-200005150-00014.

Immune response and myoblasts that express Fas ligand.

Science. 1997 Nov 14;278(5341):1322-4. doi: 10.1126/science.278.5341.1322.

Mechanisms of accelerated immune-mediated diabetes resulting from islet beta cell expression of a Fas ligand transgene.胰岛β细胞表达Fas配体转基因导致免疫介导性糖尿病加速的机制。

J Immunol. 2003 May 15;170(10):4996-5002. doi: 10.4049/jimmunol.170.10.4996.

Prolongation of allograft survival of transfected islets expressing human CTLA4-Ig, human soluble Fas ligand or a combination of the two.表达人CTLA4-Ig、人可溶性Fas配体或两者组合的转染胰岛的同种异体移植物存活期延长。

Transplant Proc. 1998 Mar;30(2):534. doi: 10.1016/s0041-1345(97)01393-6.

Fas ligand on tumor cells mediates inactivation of neutrophils.肿瘤细胞上的Fas配体介导中性粒细胞失活。

J Immunol. 2003 Aug 1;171(3):1183-91. doi: 10.4049/jimmunol.171.3.1183.

The role of FAS/FASLig and apoptosis in beta-cell death in animal models: relevance for human IDDM.FAS/FAS配体及细胞凋亡在动物模型β细胞死亡中的作用：与人类胰岛素依赖型糖尿病的相关性

Diabetes Metab Rev. 1998 Jun;14(2):194-5. doi: 10.1002/(sici)1099-0895(199806)14:2<194::aid-dmr8210>3.0.co;2-v.

Fas/Apo-1 (CD95)-mediated apoptosis of neutrophils with Fas ligand (CD95L)-expressing tumors is crucial for induction of inflammation by neutrophilic polymorphonuclear leukocytes associated with antitumor immunity.Fas/Apo-1（CD95）介导的中性粒细胞凋亡与表达Fas配体（CD95L）的肿瘤有关，这对于嗜中性多形核白细胞诱导与抗肿瘤免疫相关的炎症至关重要。

Cell Immunol. 2001 Jan 10;207(1):41-8. doi: 10.1006/cimm.2000.1734.

引用本文的文献

Tumor evasion from T cell surveillance.肿瘤对T细胞监视的逃逸。

J Biomed Biotechnol. 2011;2011:918471. doi: 10.1155/2011/918471. Epub 2011 Nov 15.

Fas/CD95 deficiency in ApcMin/+ mice increases intestinal tumor burden.Fas/CD95 缺陷型 ApcMin/+ 小鼠的肠道肿瘤负担增加。

PLoS One. 2010 Feb 5;5(2):e9070. doi: 10.1371/journal.pone.0009070.

Fas ligand exerts its pro-inflammatory effects via neutrophil recruitment but not activation.Fas配体通过募集而非激活中性粒细胞发挥其促炎作用。

Immunology. 2007 Jan;120(1):133-9. doi: 10.1111/j.1365-2567.2006.02504.x.

Natural selection of tumor variants in the generation of "tumor escape" phenotypes.肿瘤逃逸表型产生过程中肿瘤变体的自然选择。

Nat Immunol. 2002 Nov;3(11):999-1005. doi: 10.1038/ni1102-999.

Accelerating the induction of Fas-mediated T cell apoptosis: a strategy for transplant tolerance?加速Fas介导的T细胞凋亡的诱导：一种实现移植耐受的策略？

Clin Exp Immunol. 2001 Dec;126(3):589-97. doi: 10.1046/j.1365-2249.2001.01706.x.

Not so Fas: Re-evaluating the mechanisms of immune privilege and tumor escape.并非如此简单：重新评估免疫豁免和肿瘤逃逸机制。

Nat Med. 2000 May;6(5):493-5. doi: 10.1038/74955.

Human melanoma cells do not express Fas (Apo-1/CD95) ligand.人黑色素瘤细胞不表达Fas（Apo-1/CD95）配体。

Cancer Res. 1999 Jan 1;59(1):59-62.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验