Givre S J, Mindel J S
Department of Ophthalmology, Mount Sinai Medical Center, New York, New York 10029-6574, USA.
J Neuroophthalmol. 1998 Mar;18(1):32-5.
A 37-year-old man with a history of sarcoidosis, hypertension, asthma, depression and prior intravenous drug use presented with complaints of difficulty in finding his way around the house, headache, and blurred vision in both eyes. The symptoms had been increasing in severity over the prior several months. Physical examination showed normal visual acuity, pupil reactions, and fundi but severe, circumferential constriction of the visual fields bilaterally. The visual fields enlarged appropriately on increasing the distance from the patient to the tangent screen. Neuroimaging revealed bilateral, occipital meningeal involvement and parenchymal lesions consistent with sarcoidosis. Treatment with oral corticosteroids produced a mild subjective improvement in the patient's symptoms and stabilized the visual fields, without improving them. This case represents an unusual presentation of presumed neurosarcoidosis involving the visual pathways at the level of the occipital lobes.
一名37岁男性,有结节病、高血压、哮喘、抑郁症病史,既往有静脉注射毒品史,现出现在家中迷路困难、头痛及双眼视力模糊的症状。在过去几个月里,这些症状的严重程度不断增加。体格检查显示视力、瞳孔反应和眼底正常,但双侧视野严重环形缩窄。当增加患者与切线屏的距离时,视野会适当扩大。神经影像学检查显示双侧枕部脑膜受累及与结节病相符的实质病变。口服糖皮质激素治疗使患者症状有轻度主观改善,视野稳定,但未改善。该病例代表了一种罕见的推测为神经结节病的表现,累及枕叶水平的视觉通路。