Aboutaieb R, Dakir M, Sarrf I, el Moussaoui A, Bennani S, el Mrini M, Meziane F, Benjelloun S
Service d'Urologie, CHU IBN Rochd, Casablanca, Maroc.
Prog Urol. 1998 Feb;8(1):43-6.
Bladder tumours classically affect the elderly, but can also occur in young adults. The authors studied the prognosis of these tumours in patients under the age of 40. In their experience, these tumours represent 3.27% of all bladder tumours. 26 patients with a mean age of 34 years (20-40 years), 8 under the age of 30, were studied. There was a marked male predominance (23 males, 3 females). The tumour was a transitional cell carcinoma in 25 cases and a squamous cell carcinoma in 1 case. It was superficial in 11 cases and invasive in 15 cases. Transurethral resection and cystectomy were performed in 9 cases of superficial tumours and 11 cases of invasive tumours, respectively. In the group of superficial tumours, a favourable course was observed in 7 cases, with 3 cases of recurrence and 1 case of progression. In the group of invasive tumours, a favourable course was observed in 6 cases, recurrence was observed in 2 cases and 5 patients died. Superficial tumours therefore have a better prognosis in subjects under the age of 30. Invasive tumours are more frequent and often advanced, suggesting a marked potential for progression. Their prognosis depends on tumour stage, and is not correlated with age.
膀胱肿瘤典型地好发于老年人,但也可发生于年轻人。作者研究了40岁以下患者这些肿瘤的预后情况。根据他们的经验,这些肿瘤占所有膀胱肿瘤的3.27%。研究了26例平均年龄34岁(20 - 40岁)的患者,其中8例年龄在30岁以下。男性明显居多(23例男性,3例女性)。25例肿瘤为移行细胞癌,1例为鳞状细胞癌。11例为浅表性肿瘤,15例为浸润性肿瘤。9例浅表性肿瘤和11例浸润性肿瘤分别进行了经尿道切除术和膀胱切除术。在浅表性肿瘤组中,7例病程良好,3例复发,1例进展。在浸润性肿瘤组中,6例病程良好,2例复发,5例患者死亡。因此,浅表性肿瘤在30岁以下患者中预后较好。浸润性肿瘤更常见且往往处于进展期,提示有明显的进展潜能。其预后取决于肿瘤分期,与年龄无关。