Baquero M, Yayá-Huamán R
Servicio de Neurología, Hospital Universitari La Fe, Valencia, España.
Rev Neurol. 1998 Jan;26(149):143-8.
Vertebro-basilar dolichoectasia is an anomaly which has been well-known since the earliest days of clinical neurology. In spite of this neither the mechanism by which it is produced not its clinical importance are fully defined. In this paper we review basic clinical aspects of this pathology.
In most cases the subjacent arteriopathy is arteriosclerotic. The clinical features are very varied and it may be asymptomatic. Sometimes the clinical findings are due to compression of adjacent structures, basically the cranial nerves. Trigeminal neuralgia and hemifacial spasm are the commonest findings. There is usually only one presenting symptom but several symptoms may occur at the same time. On other occasions the patients present with cognitive deficits; there is no obvious relationship of cause and effect between vertebro-basilar dolichoectasia and cognitive deterioration. Finally, there seems to be a predisposition to cerebrovascular accidents. Most cerebrovascular accidents associated with dolichoectasia are ischemic, although some are hemorrhagic. Nevertheless, from the point of view of prognosis, the importance of vertebro-basilar dolichoectasia is not completely clear. At the present time, there are no therapeutic attitudes which are specific for this anomaly.
Further studies of the practical results of detection of this anomaly and its natural history are necessary.
椎基底动脉延长扩张症是一种自临床神经学早期就已为人熟知的异常情况。尽管如此,其形成机制及其临床重要性均未完全明确。在本文中,我们回顾了这种病理状况的基本临床方面。
在大多数情况下,其 underlying 动脉病变是动脉硬化性的。临床特征非常多样,可能无症状。有时临床发现是由于对相邻结构的压迫,主要是颅神经。三叉神经痛和半面痉挛是最常见的表现。通常只有一种主要症状,但也可能同时出现多种症状。在其他情况下,患者会出现认知缺陷;椎基底动脉延长扩张症与认知衰退之间没有明显的因果关系。最后,似乎存在脑血管意外的易感性。与延长扩张症相关的大多数脑血管意外是缺血性的,尽管有些是出血性的。然而,从预后的角度来看,椎基底动脉延长扩张症的重要性尚不完全清楚。目前,对于这种异常情况没有特定的治疗方法。
有必要进一步研究这种异常情况的检测实际结果及其自然病史。