Clarke M, Halil T, Salmon N
Br J Prev Soc Med. 1976 Jun;30(2):115-22. doi: 10.1136/jech.30.2.115.
Estimates of the population prevalence of peptic and duodenal ulceration in men aged between 25 and 64 years were made in the London borough of Lambeth. The sampling frame for these estimates was a 20% private census. The lifetime prevalence rate of proved peptic ulcer (haematemesis, gastric and duodenal ulcers as validated by operation or barium meal), adjusted for age and social class, was estimated to be 6-7%, while the similarly adjusted lifetime prevalence for duodenal ulcer was 4-4%. The lifetime prevalences increased with age but not significantly so. A social class gradient was demonstrated with the highest prevalence in social class I and II. Previously described associations with blood group, secretor status, and serum pepsinogen were confirmed. Reported use of medical services increased with increasing severity of symptoms. A large number of respondents, however, who reported symptoms reported no medical care. It seemed unlikely that those men who reported symptoms and no medical care had demonstrable peptic ulcers.
在伦敦朗伯斯区,对年龄在25至64岁之间男性的消化性溃疡和十二指肠溃疡的人群患病率进行了估算。这些估算的抽样框架是20%的私人人口普查。经年龄和社会阶层调整后,经证实的消化性溃疡(呕血、经手术或钡餐证实的胃溃疡和十二指肠溃疡)的终生患病率估计为6%-7%,而同样经调整的十二指肠溃疡终生患病率为4%-4%。终生患病率随年龄增长而增加,但增幅不显著。呈现出社会阶层梯度,社会阶层I和II的患病率最高。先前描述的与血型、分泌状态和血清胃蛋白酶原的关联得到了证实。报告的医疗服务使用情况随症状严重程度的增加而增加。然而,大量报告有症状的受访者并未接受医疗护理。那些报告有症状但未接受医疗护理的男性似乎不太可能患有可证实的消化性溃疡。