Fedrick J
Br J Prev Soc Med. 1976 Jun;30(2):132-7. doi: 10.1136/jech.30.2.132.
Data relating to the incidence of anencephalus for the 12-year period 1961-72 were abstracted from the Statistical Reviews of the Registrar General for Scotland. It was shown that considerable geographical variation is still apparent with the highlands having, in general, the lower incidences. In comparison with the earlier study of Edwards (1958), there were some changes: the incidence in the areas to the west had increased and that in those to the east decreased. During the 12-year period there was an overall decline in the incidence of the lesion; this was most marked in births to women under 20 years, and to those of social classes III, IV, and V. The decline was least apparent for births to women of high social class and the unmarried. It was shown that there was little seasonal variation in the time of delivery, but that even when the trend had been taken into account the yearly fluctuation was significantly different from that expected, with an excess of cases in 1961 and 1971.
1961年至1972年这12年间无脑儿发病率的数据摘自苏格兰总登记官的统计回顾。结果显示，显著的地理差异依然明显，总体而言，高地地区的发病率较低。与爱德华兹（1958年）早期的研究相比，出现了一些变化：西部地区的发病率上升，而东部地区的发病率下降。在这12年期间，该病变的发病率总体呈下降趋势；这在20岁以下女性以及社会阶层为III、IV和V的女性所生育的婴儿中最为明显。社会阶层较高和未婚女性所生育婴儿的发病率下降最不明显。结果表明，分娩时间的季节性变化不大，但即使考虑了趋势因素，每年的波动仍与预期有显著差异，1961年和1971年的病例数过多。
