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两名接受自体外周血祖细胞移植(PBPCT)的儿童巨细胞病毒肺炎后的生存情况。

Survival after cytomegalovirus pneumonia in two children receiving autologous peripheral blood progenitor cell transplantation (PBPCT).

作者信息

Castagnola E, Dallorso S, Rabagliati M, Sacco O, Kotitsa Z, Dini G

机构信息

Unit of Infectious Diseases, G Gaslini Children's Hospital, Genoa, Italy.

出版信息

Bone Marrow Transplant. 1998 Mar;21(5):529-31. doi: 10.1038/sj.bmt.1701121.

Abstract

Cytomegalovirus (CMV) pneumonia is a very rare but often fatal complication of autologous bone marrow or peripheral blood progenitor cell transplantation. Diagnosis is usually made by means of CMV antigenemia which is strongly predictive of CMV disease. We describe two cases of PBPC transplantation who survived after CMV pneumonia which was diagnosed only by bronchoalveolar lavage in the absence of CMV-antigenemia.

摘要

巨细胞病毒(CMV)肺炎是自体骨髓或外周血祖细胞移植非常罕见但往往致命的并发症。诊断通常通过CMV抗原血症进行,CMV抗原血症对CMV疾病具有很强的预测性。我们描述了两例外周血祖细胞移植患者,他们在发生CMV肺炎后存活下来,其CMV肺炎仅通过支气管肺泡灌洗诊断,而当时并无CMV抗原血症。

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