Immunohistochemical localization of leptin receptor in the rat brain.
作者信息
Shioda S, Funahashi H, Nakajo S, Yada T, Maruta O, Nakai Y
机构信息
Department of Anatomy, Showa University School of Medicine, Tokyo, Japan.
出版信息
Neurosci Lett. 1998 Feb 27;243(1-3):41-4. doi: 10.1016/s0304-3940(98)00082-2.
PMID:9535108
Abstract
The distribution of leptin receptor in the rat brain was determined by immunocytochemistry and Western blotting. Strong leptin receptor immunoreactivity was detected in the arcuate, paraventricular and ventromedial nuclei of the hypothalamus, and lateral hypothalamic area. The olfactory bulb, neocortex, cerebellar cortex, dorsal raphe nucleus, inferior olive nucleus, nucleus of the solitary tract, dorsal motor nucleus of the vagus nerve also showed intense immunoreactivity. Western blotting analysis yielded a 120-kDa major band.
摘要
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