Goldacre M J, Miller D L
Br Med J. 1976 Aug 28;2(6034):501-3. doi: 10.1136/bmj.2.6034.501.
Several different sources of data, including statutory notifications, were used to identify cases of acute bacterial meningitis in childhood in a defined population. Only half the cases of meningococcal meningitis and less than one quarter of ofther types of bacterial meningitis had been notified. Notified cases differed from the remainder with respect to causative organism, age, outcome, and type of hospital of admission. Thus notifications are an unreliable measure of incidence for this disease, and studies of infectious disease based on notified cases alone should be interpreted with considerable reserve. It is suggested that infectious-disease surveillance should be both clinical and microbiological and that data from different sources need to co-ordinated. The reason for reporting each disease (or organism) should be specified and and reviewed periodically.
利用包括法定通报在内的几种不同数据来源,在特定人群中识别儿童急性细菌性脑膜炎病例。仅一半的脑膜炎球菌性脑膜炎病例以及不到四分之一的其他类型细菌性脑膜炎病例得到了通报。通报病例在致病生物体、年龄、转归及收治医院类型方面与其余病例有所不同。因此,通报是该疾病发病率的不可靠衡量指标,仅基于通报病例的传染病研究应谨慎解读。建议传染病监测应兼具临床和微生物学监测,且不同来源的数据需要进行协调。应明确每种疾病(或生物体)的报告原因并定期进行审查。