Vassallo M, Allen S C
Department of Medicine, Royal Bournemouth Hospital, UK.
Int J Clin Pract. 1997 Oct;51(7):438-41.
People recovering from pneumonia are often weak for no apparent reason. Clinical features such as postural hypotension, arrhythmia and syndrome of inappropriate ADH have, in other circumstances, been attributed to impaired autonomic function. The aim of this study was to see whether elderly patients with pneumonia had impaired autonomic cardiovascular reflexes and, if so, how long this persisted. We compared healthy elderly controls, elderly controls with trauma (fractured femoral neck) and elderly patients with pneumonia. Thirty-eight subjects were studied in a series of cardiovascular autonomic function tests. Results suggest that elderly people have a high prevalence of impaired cardiovascular autonomic reflexes in the immediate post-pneumonic phase, and that this improves significantly after six weeks, with a further improvement by six months. Elderly patients recovering from pneumonia are predisposed to the adverse effects of drugs and other factors which can further impair autonomic cardiovascular reflexes.
肺炎康复期的患者常常毫无明显原因地身体虚弱。在其他情况下，诸如体位性低血压、心律失常和抗利尿激素分泌异常综合征等临床特征被认为与自主神经功能受损有关。本研究的目的是观察老年肺炎患者是否存在自主心血管反射受损，若存在，这种情况会持续多久。我们比较了健康老年对照组、有创伤（股骨颈骨折）的老年对照组和老年肺炎患者。对38名受试者进行了一系列心血管自主神经功能测试。结果表明，老年患者在肺炎急性期后心血管自主神经反射受损的发生率较高，六周后这种情况显著改善，六个月后进一步改善。从肺炎中康复的老年患者易受药物和其他因素的不良影响，这些因素会进一步损害自主心血管反射。
