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血液透析通路手术后手部缺血患者的发病率及特征

Incidence and characteristics of patients with hand ischemia after a hemodialysis access procedure.

作者信息

Morsy A H, Kulbaski M, Chen C, Isiklar H, Lumsden A B

机构信息

Department of Surgery, Veterans Affairs Medical Center, Decatur, Georgia, USA.

出版信息

J Surg Res. 1998 Jan;74(1):8-10. doi: 10.1006/jsre.1997.5206.

Abstract

The purpose of this study was to determine the clinical characteristics of chronic renal failure patients who developed hand ischemia in the limb carrying the dialysis angioaccess. A retrospective review of the charts of 352 patients who underwent 409 upper extremity arteriovenous access, and who were subsequently diagnosed as steal syndrome, was performed at the Emory University Hospital between February 1992 and January 1997. Hand ischemia occurred after 13 of 299 arteriovenous grafts (4.3%) and after 2 of 110 direct forearm arteriovenous fistulas (1.8%). Six patients developed ischemic manifestations immediately postoperatively, 2 in the first week, 4 after 1 month, and 1 after 1 year. Thirteen occurred in association with the primary access procedure. Two cases occurred following graft thrombectomy and outflow dilatation. Seven patients were mildly symptomatic with dialysis-induced pain, coldness, or numbness; 8 patients developed severe ischemic manifestations in the form of sensory loss in 3, severe intolerable pain with impalpable pulse in 3, and digital gangrene and amputation in 2, one of whom developed an unhealed amputation stump and required a higher amputation level with satisfactory healing of the revised stump. Three patients were treated conservatively, 6 by banding, 4 by ligation, 1 by embolization, and 1 by distal ligation and bypass operation. Clinical characteristics of patients with hand ischemia included long-standing insulin-dependent diabetes (10), chronic hypertension (12), peripheral arterial disease (14; 93.3%), coronary artery disease (8), and systemic lupus erythematosis (1). Severe peripheral arterial diseases are commonly found and may be markers for risk of hand ischemia after access surgery.

摘要

本研究的目的是确定在携带透析血管通路的肢体中发生手部缺血的慢性肾衰竭患者的临床特征。1992年2月至1997年1月期间,在埃默里大学医院对352例行409次上肢动静脉通路手术且随后被诊断为窃血综合征的患者病历进行了回顾性研究。299例动静脉移植物中有13例(4.3%)、110例直接前臂动静脉瘘中有2例(1.8%)发生了手部缺血。6例患者术后立即出现缺血表现,2例在第一周出现,4例在1个月后出现,1例在1年后出现。13例与初次通路手术相关。2例发生在移植物血栓切除术和流出道扩张术后。7例患者有轻微症状,表现为透析引起的疼痛、发冷或麻木;8例患者出现严重缺血表现,其中3例感觉丧失,3例脉搏触不到伴严重难以忍受的疼痛,2例手指坏疽并截肢,其中1例截肢残端未愈合,需要提高截肢平面,修订后的残端愈合良好。3例患者接受保守治疗,6例采用绑扎术,4例采用结扎术,1例采用栓塞术,1例采用远端结扎和旁路手术。手部缺血患者的临床特征包括长期胰岛素依赖型糖尿病(10例)、慢性高血压(12例)、外周动脉疾病(14例;93.3%)、冠状动脉疾病(8例)和系统性红斑狼疮(1例)。严重外周动脉疾病很常见,可能是通路手术后手部缺血风险的标志物。

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