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白癜风患者的色素再生。通过超薄移植物进行黑素细胞移植。

Repigmentation in vitiligo patients. Melanocyte transfer via ultra-thin grafts.

作者信息

Kahn A M, Cohen M J

机构信息

Department of Surgery, UCLA Medical Center, USA.

出版信息

Dermatol Surg. 1998 Mar;24(3):365-7.

PMID:9537012
Abstract

BACKGROUND

Several years ago, a successful surgical technique for treating depigmentation resulting from burn injuries was developed.

OBJECTIVE

The purpose of this study was to investigate results of dermabrasion with melanocyte transplantation using new modifications of the technique in patients with vitiligo.

METHODS

We performed 17 procedures on 12 patients with stable vitiligo. The epithelium of the vitiliginous areas was removed by dermabrasion. The dermabraded area was then reepithelialized with ultra-thin sheet grafts, which more recently were meshed and partially expanded.

RESULTS

Good to excellent repigmentation was observed in 88% of the procedures. Scarring did not develop in the repigmented or donor site regions. The final color match has been good to excellent.

CONCLUSIONS

This technique has proven beneficial in 88% of the procedures on our patients. Both our patients and we feel that this provides a valuable treatment option in patients who have failed medical management.

摘要

背景

数年前,一种成功治疗烧伤后色素脱失的手术技术被研发出来。

目的

本研究旨在探讨采用该技术的新改良方法对白癜风患者进行磨皮联合黑素细胞移植的效果。

方法

我们对12例稳定期白癜风患者实施了17次手术。通过磨皮去除白癜风区域的上皮。然后用超薄皮片对磨皮区域进行再上皮化,这些皮片最近经过了网状化处理并部分扩张。

结果

88%的手术观察到色素恢复良好至极佳。色素恢复区域或供皮区均未出现瘢痕形成。最终的肤色匹配良好至极佳。

结论

该技术在我们患者的88%的手术中已证明是有益的。我们的患者和我们都认为,这为药物治疗失败的患者提供了一种有价值的治疗选择。

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