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“非保护”性左主干冠状动脉狭窄的支架置入术:早期和晚期结果

Stenting of "unprotected" left main coronary artery stenoses: early and late results.

作者信息

Laruelle C J, Brueren G B, Ernst S M, Bal E T, Mast G E, Suttorp M J, Brutel de la Rivière A, Plokker T H

机构信息

Department of Interventional Cardiology and Cardiothoracic Surgery, St Antonius Hospital Koekoekslaan, Netherlands.

出版信息

Heart. 1998 Feb;79(2):148-52. doi: 10.1136/hrt.79.2.148.

Abstract

OBJECTIVE

To assess short and long term efficacy of coronary stent implantation for unprotected left main coronary artery stenosis.

DESIGN

Retrospective follow up study.

SETTING

Tertiary referral centre for interventional cardiology and cardiac surgery.

PATIENTS

Eighteen consecutive patients (12 men; age 70.8 years) between May 1993 and July 1996. Ten patients presented with stable angina and underwent the procedure electively, eight patients presented either with unstable angina or myocardial infarction and underwent the procedure in emergency.

INTERVENTION

Johnson and Johnson Palmaz-Schatz stents were used in 16 patients, and a Microstent and a Gianturco-Roubin in one patient each. An intra-aortic balloon pump was prophylactively used for two patients in the elective group. In the acute group, six required an intra-aortic balloon pump.

MAIN OUTCOME MEASURES

Procedural success rate and major adverse cardiac events.

RESULTS

Successful stent implantation was achieved in all patients. In the elective group, no major adverse cardiac event occurred during the procedure, but one patient had to undergo repeated angioplasty before discharge. All patients of the elective group were discharged alive and there has been one non-cardiac death during a follow up of (mean (SD)) 10 (4) months. In the emergency group, one patient died during the procedure, one patient developed a non Q-wave myocardial infarction, one patient underwent emergency coronary bypass surgery, while another patient died suddenly before hospital discharge. Six patients of the emergency group were discharged alive and there has been one non-cardiac death during a follow up of 7 (4) months.

CONCLUSIONS

Elective stent implantation for unprotected left main coronary artery stenosis is safe and effective in selected stable patients. Urgent stent implantation, however, cannot be considered as a definitive procedure in emergency situation.

摘要

目的

评估冠状动脉支架植入术治疗无保护左主干冠状动脉狭窄的短期和长期疗效。

设计

回顾性随访研究。

地点

介入心脏病学和心脏外科三级转诊中心。

患者

1993年5月至1996年7月期间连续收治的18例患者(12例男性;年龄70.8岁)。10例患者表现为稳定型心绞痛,择期接受该手术;8例患者表现为不稳定型心绞痛或心肌梗死,急诊接受该手术。

干预措施

16例患者使用强生公司的帕尔马兹-施查茨支架,1例患者使用微支架,1例患者使用朱安图尔科-鲁宾支架。择期组中有2例患者预防性使用了主动脉内球囊泵。急性组中有6例患者需要使用主动脉内球囊泵。

主要观察指标

手术成功率和主要不良心脏事件。

结果

所有患者均成功植入支架。择期组在手术过程中未发生主要不良心脏事件,但有1例患者在出院前不得不接受再次血管成形术。择期组所有患者均存活出院,在平均(标准差)10(4)个月的随访期间有1例非心脏死亡。急诊组中有1例患者在手术过程中死亡,1例患者发生非Q波心肌梗死,1例患者接受了急诊冠状动脉搭桥手术,另1例患者在出院前突然死亡。急诊组中有6例患者存活出院,在7(4)个月的随访期间有1例非心脏死亡。

结论

对于选定的稳定患者,择期植入支架治疗无保护左主干冠状动脉狭窄是安全有效的。然而,在紧急情况下,紧急植入支架不能被视为确定性手术。

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