el-Saggan A, Bang G, Olofsson J
Department of Otolaryngology-Head and Neck Surgery, Haukeland University Hospital, Bergen, Norway.
J Laryngol Otol. 1998 Jan;112(1):61-4. doi: 10.1017/s0022215100139908.
Melanotic neuroectodermal tumour of infancy is an uncommon neoplasm that usually occurs in children aged one year or less. Difficulty in deciding the cellular origin of this tumour has led to numerous names, including congenital melanocarcinoma, melanotic epithelial odontoma, melanotic ameloblastoma, and retinal anlage tumour. Electron microscopy and histochemical studies, however, have now established the neural crest origin. The most frequent site of occurrence is the maxilla followed by the skull, the brain and the mandible. The genital organs are the most frequent extracranial site. We present two cases of melanotic neuroectodermal tumour of infancy arising in the maxilla.
婴儿黑色素性神经外胚层肿瘤是一种罕见的肿瘤，通常发生在1岁及以下的儿童。确定该肿瘤的细胞起源存在困难，导致其有众多名称，包括先天性黑色素癌、黑色素上皮性牙瘤、黑色素成釉细胞瘤和视网膜原基肿瘤。然而，电子显微镜和组织化学研究现已证实其起源于神经嵴。最常见的发生部位是上颌骨，其次是颅骨、脑和下颌骨。生殖器官是最常见的颅外部位。我们报告两例发生在上颌骨的婴儿黑色素性神经外胚层肿瘤。
