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脊柱肿瘤的治疗。

Treatment of tumors of the spine.

作者信息

Ozaki T, Halm H, Liljenqvist U, Winkelmann W

机构信息

Department of Orthopaedics, Westfälische Wilhelms-University, Münster, Germany.

出版信息

Hiroshima J Med Sci. 1997 Dec;46(4):125-31.

PMID:9538562
Abstract

Thirty-one patients with spinal tumors underwent reconstructive surgery with our spinal instrumentation system (MPDS and MADS), with or without our new vertebral tumor prosthesis. The characteristics of the spinal tumors were analysed statistically and the treatment outcome was evaluated. There were 4 benign tumors, 6 malignant tumors, and 21 metastatic tumors. The malignant tumors involved the sacrum more frequently than the benign tumors (p = 0.0098). Metastatic tumors involved the thoracic spine more frequently than benign or malignant tumors (p = 0.0161). The average number of affected vertebrae was 1.2 in the benign tumors, 1.8 in the malignant tumors, and 2.4 in the metastatic tumors. The metastatic tumors had a tendency to involve the anterior or middle part of the spine more frequently than the benign or malignant tumors (statistically not significant). After surgery, neurological improvement was noted in 8 patients, nochange in 19 patients, and impairment due to resection of the nerve roots in sacral tumors in 4 patients.

摘要

31例脊柱肿瘤患者接受了使用我们的脊柱内固定系统(MPDS和MADS)的重建手术,部分患者还使用了我们新的椎体肿瘤假体。对脊柱肿瘤的特征进行了统计分析,并评估了治疗结果。其中有4例良性肿瘤、6例恶性肿瘤和21例转移性肿瘤。恶性肿瘤累及骶骨的频率高于良性肿瘤(p = 0.0098)。转移性肿瘤累及胸椎的频率高于良性或恶性肿瘤(p = 0.0161)。良性肿瘤受累椎体的平均数量为1.2个,恶性肿瘤为1.8个,转移性肿瘤为2.4个。转移性肿瘤累及脊柱前部或中部的倾向高于良性或恶性肿瘤(统计学上无显著性差异)。术后,8例患者神经功能改善,19例患者无变化,4例患者因骶骨肿瘤神经根切除而出现神经功能损害。

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