Błasiak M, Otrebski S, Pacyk G
Oddziału Wewnetrznego Wojewódzkiego Szpitala Zespolonego im. Prof. W. Orłowskiego w Czestochowie.
Pol Merkur Lekarski. 1997 Feb;2(8):107-8.
Heart rate variability is a useful prognostic parameter in patients with coronary artery disease. SDNN (standard deviation of all normal RR intervals in the entire ECG 24 hour recording) was evaluated in patients with acute myocardial infarction (AMI), who were divided in two groups: The first group consisted of 22 patients who had not received streptokinase; in the second group there were 10 patients, who were treated with streptokinase and in whom indirect reperfusion criteria were observed. Two control groups were drawn into the study: the third included 30 patients with stable ischaemic heart disease with no history of myocardial infarction and the fourth group of 18 healthy subjects. SDNN was calculated by the ECG Mediarc Premier II Holter System (DRG International Inc., NJ, USA) in the time domain from 24 hour ECG recordings. Mean SDNN divided by standard deviation values were: I: 88.1 divided by 25.1 ms; II: 96.7 divided by 24.3 ms; III: 107.5 divided by 22.6 ms; IV: 136.0 divided by 20.4 ms. No significant difference in SDNN was found between heart infarct patients, who were and were not thrombolyzed (96.7 divided by 24.3 ms vs. 88.1 divided by 25.6 ms; p > 0.05) as well as between thrombolyzed infarct patients and patients with stable ischaemic heart disease with no history of myocardial infarction (96.7 divided by 24.3 ms vs. 107.5 divided by 22.6 ms; p > 0.05). However, a significant difference in SDNN was observed between patients who had not been thrombolyzed and patients with stable ischaemic heart disease (88.1 divided by 25.6 ms vs. 107.5 divided by 22.6 ms; p < 0.01).
心率变异性是冠心病患者一项有用的预后参数。对急性心肌梗死（AMI）患者的全部正常RR间期（整个24小时心电图记录中的）标准差（SDNN）进行了评估，这些患者被分为两组：第一组由22例未接受链激酶治疗的患者组成；第二组有10例患者，他们接受了链激酶治疗且符合间接再灌注标准。研究纳入了两个对照组：第三组包括30例无心肌梗死病史的稳定型缺血性心脏病患者，第四组为18名健康受试者。通过ECG Mediarc Premier II动态心电图系统（美国新泽西州DRG国际公司）在时域中根据24小时心电图记录计算SDNN。平均SDNN除以标准差的值分别为：第一组：88.1除以25.1毫秒；第二组：96.7除以24.3毫秒；第三组：107.5除以22.6毫秒；第四组：136.0除以20.4毫秒。接受和未接受溶栓治疗的心肌梗死患者之间（96.7除以24.3毫秒对88.1除以25.6毫秒；p>０.05）以及溶栓治疗的心肌梗死患者和无心肌梗死病史的稳定型缺血性心脏病患者之间（96.7除以24.3毫秒对107.5除以22.6毫秒；p>０.05）的SDNN均未发现显著差异。然而，未接受溶栓治疗的患者与稳定型缺血性心脏病患者之间的SDNN存在显著差异（88.1除以25.6毫秒对107.5除以22.6毫秒；p<０.01）。
