Gordin V A, Nedospasov A A
Hydrometeorological Centre of Russia, Moscow.
FEBS Lett. 1998 Mar 13;424(3):239-42. doi: 10.1016/s0014-5793(98)00164-1.
Micellar catalysis plays a crucial role in NO metabolism because media in vivo are heterogeneous and the concentration of NO in different phases at different levels of solubility differs by degrees of magnitude. The relative volumes of the hydrophobic phases are usually small. At small volumes (which are calculated) of these phases the reaction rates of NO metabolism change. The dependence on the relative volumes is resonance-like. Not only regulation, but bifurcations and catastrophes are possible in vivo as a result of this changing due to the small change of effectiveness of micellar catalysis.
胶束催化在一氧化氮（NO）代谢中起着至关重要的作用，因为体内介质是异质的，并且在不同溶解度水平下不同相中的NO浓度在数量级上存在差异。疏水相的相对体积通常较小。在这些相的小体积（经计算）下，NO代谢的反应速率会发生变化。对相对体积的依赖性呈共振状。由于胶束催化效率的微小变化导致这种变化，体内不仅可能发生调节，还可能出现分岔和灾变。
